Suspected Recurrence of Cranial Neuralgia Following Infection With SARS-CoV-2: A Case Report.

It is understood that patients infected with the COVID-19 virus can present with headache as an initial symptom, but it is unclear if those with a history of cranial neuralgias may have a different initial COVID-19 presentation, or if infections from SARS-CoV-2 virus may cause a recurrence of previous cranial neuralgias. In this review, we report a case of cranial neuralgia recurrence that was preceded by a SARS-CoV-2 exposure. There is currently a lack of literature describing COVID-19 patients with a recurrence of a previous cranial neuralgia, and this case draws attention to potential reactivation of cranial neuralgia symptoms in COVID-19 patients, highlights key components of the pathophysiology of cranial neuralgias, and underscores the potential need to identify previous history of cranial neuralgia to more appropriately navigate management and treatment of neuralgia causing head pain as a consequence of COVID-19 infection.