Literature DB >> 35701727

"The Disease Awareness Innovation Network" for chronic kidney disease identification in general practice.

Francesco Pesce1, Domenico Pasculli2, Giuseppe Pasculli3,4, Luca De Nicola5, Mario Cozzolino6, Antonio Granata7, Loreto Gesualdo8.   

Abstract

BACKGROUND: The "awareness gap" and the under-recognition of chronic kidney disease (CKD) by general practitioners (GPs) is well documented. We set a framework to evaluate the impact in primary care of targeted training and networking with nephrologists with regard to CKD awareness in terms of potential increase of the proportion of patients classified according to KDIGO in the general population and in patients with diabetes, hypertension and heart failure.
METHODS: Data were extracted from the Millewin Digital Platform in use by the GPs (N = 17) at baseline (T0, N = 17,854) and after 6 months (T6, N = 18,662) of networking (education, instant messaging and selected joint visits) with nephrologists (N = 2). The following variables were extracted: age, sex, eGFR (estimated glomerular filtration rate), ACR (urinary albumin-to-creatinine ratio), presence of type 2 diabetes, hypertension and heart failure. The proportion of patients detected having an eGFR below 60 mL/min/1.73m2 was also reported as deemed clinically relevant.
RESULTS: We observed an increase in the use of ACR and eGFR tests in the entire cohort (+ 121% and + 73%, respectively) and in patients with comorbidities. The proportion of patients with eGFR < 60 mL/min/1.73m2 significantly increased from 2.2% to 3.8% in the entire cohort,  from 6.3% to 12.7% in patients with diabetes, and from 5.6% to 9.9% in those with hypertension and finally from 10.8% to 23.7% in patients with heart failure.
CONCLUSIONS: Training and network support to GPs by nephrologists can improve CKD awareness and increase its identification in the general population and, even more, in categories at risk.
© 2022. The Author(s).

Entities:  

Keywords:  Awareness; Chronic kidney disease; Early diagnosis; Primary care

Mesh:

Substances:

Year:  2022        PMID: 35701727      PMCID: PMC9584961          DOI: 10.1007/s40620-022-01353-6

Source DB:  PubMed          Journal:  J Nephrol        ISSN: 1121-8428            Impact factor:   4.393


  30 in total

1.  CKD Prevalence Varies across the European General Population.

Authors:  Katharina Brück; Vianda S Stel; Giovanni Gambaro; Stein Hallan; Henry Völzke; Johan Ärnlöv; Mika Kastarinen; Idris Guessous; José Vinhas; Bénédicte Stengel; Hermann Brenner; Jerzy Chudek; Solfrid Romundstad; Charles Tomson; Alfonso Otero Gonzalez; Aminu K Bello; Jean Ferrieres; Luigi Palmieri; Gemma Browne; Vincenzo Capuano; Wim Van Biesen; Carmine Zoccali; Ron Gansevoort; Gerjan Navis; Dietrich Rothenbacher; Pietro Manuel Ferraro; Dorothea Nitsch; Christoph Wanner; Kitty J Jager
Journal:  J Am Soc Nephrol       Date:  2015-12-23       Impact factor: 10.121

2.  Cohort profile: The Gubbio Population Study.

Authors:  Massimo Cirillo; Oscar Terradura-Vagnarelli; Mario Mancini; Alessandro Menotti; Alberto Zanchetti; Martino Laurenzi
Journal:  Int J Epidemiol       Date:  2013-03-29       Impact factor: 7.196

3.  Early renin-angiotensin system intervention is more beneficial than late intervention in delaying end-stage renal disease in patients with type 2 diabetes.

Authors:  B Schievink; T Kröpelin; S Mulder; H-H Parving; G Remuzzi; J Dwyer; P Vemer; D de Zeeuw; H J Lambers Heerspink
Journal:  Diabetes Obes Metab       Date:  2015-11-27       Impact factor: 6.577

4.  CKD awareness and blood pressure control in the primary care hypertensive population.

Authors:  Maura Ravera; Giuseppe Noberasco; Ursula Weiss; Michela Re; Anna Maria Gallina; Alessandro Filippi; Rossella Cannavò; Giambattista Ravera; Claudio Cricelli; Giacomo Deferrari
Journal:  Am J Kidney Dis       Date:  2010-11-17       Impact factor: 8.860

5.  Value-Based Care in Chronic Kidney Disease: Missing Albuminuria is a Missed Opportunity.

Authors:  Allison C Reaves; Daniel E Weiner
Journal:  Clin J Am Soc Nephrol       Date:  2021-12-30       Impact factor: 10.614

6.  The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Authors:  Michael G Shlipak; Sri Lekha Tummalapalli; L Ebony Boulware; Morgan E Grams; Joachim H Ix; Vivekanand Jha; Andre-Pascal Kengne; Magdalena Madero; Borislava Mihaylova; Navdeep Tangri; Michael Cheung; Michel Jadoul; Wolfgang C Winkelmayer; Sophia Zoungas
Journal:  Kidney Int       Date:  2020-10-27       Impact factor: 10.612

Review 7.  International Study of Health Care Organization and Financing for renal replacement therapy in Italy: an evolving reality.

Authors:  Giuseppe Pontoriero; Pietro Pozzoni; Lucia Del Vecchio; Francesco Locatelli
Journal:  Int J Health Care Finance Econ       Date:  2007-09

Review 8.  Screening for chronic kidney disease: moving toward more sustainable health care.

Authors:  Sarah Curtis; Paul Komenda
Journal:  Curr Opin Nephrol Hypertens       Date:  2020-05       Impact factor: 2.894

9.  A diagnosis of chronic kidney disease: despite fears patients want to know early.

Authors:  Julie Wright Nunes; Meghan Roney; Eve Kerr; Akinlolu Ojo; Angela Fagerlin
Journal:  Clin Nephrol       Date:  2016-08       Impact factor: 0.975

Review 10.  Understanding the implementation of interventions to improve the management of chronic kidney disease in primary care: a rapid realist review.

Authors:  Jung Yin Tsang; Tom Blakeman; Janet Hegarty; John Humphreys; Gill Harvey
Journal:  Implement Sci       Date:  2016-04-04       Impact factor: 7.327

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