We would like to share ideas on the publication “Seroprevalence of SARS‐CoV‐2 antibodies among first‐trimester pregnant women during the second wave of the pandemic in India.
” According to Sharma et al., first‐trimester sero‐molecular screening indicates a significant incidence of COVID antibodies in the study group of pregnant women in the first trimester, even though the patients were asymptomatic.
This report may contain helpful epidemiological information. The presence of asymptomatic COVID‐19 in any population group is undeniable. A high seropositive rate can be expected in a region with a high accumulated reported number of COVID‐19 cases. In terms of antibody testing, we should still be aware of the likelihood of a false positive in endemic areas. For example, dengue fever is common in tropical endemic countries, and dengue is a probable source of SARS‐CoV‐2 antibody‐test false positives.
As a result, we must detect and evaluate the diagnostic features of antibody test kits for COVID‐19 serological research.