Literature DB >> 35698610

Strategies for Protecting Mitochondria From Metals and Chemicals.

Joseph Pizzorno.   

Abstract

Mitochondria are required for life, and dysfunction leads to chronic disease and shortened life expectancy. Unfortunately, suboptimal mitochondrial function is very common. While genetic mutations play a role, far more common is the damage from nutrient deficiencies and regular accidental and intentional exposure to mitotoxic metals and chemicals. Alcohol, antibiotics, metals, bisphenols, phthalates, pesticides and herbicides, and statins-the list is long-all impair mitochondrial function. Fortunately, toxins can be avoided and their elimination from the body can be enhanced. In addition, many natural health molecules help protect mitochondria and restore function.
Copyright © 2022 InnoVision Professional Media Inc.

Entities:  

Year:  2022        PMID: 35698610      PMCID: PMC9173845     

Source DB:  PubMed          Journal:  Integr Med (Encinitas)        ISSN: 1546-993X


  21 in total

1.  Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals.

Authors:  G Barja; A Herrero
Journal:  FASEB J       Date:  2000-02       Impact factor: 5.191

2.  Opening and closing the metabolite gate.

Authors:  Susanna Törnroth-Horsefield; Richard Neutze
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-10       Impact factor: 11.205

3.  Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in Mammalian cells.

Authors:  Sameer Kalghatgi; Catherine S Spina; James C Costello; Marc Liesa; J Ruben Morones-Ramirez; Shimyn Slomovic; Anthony Molina; Orian S Shirihai; James J Collins
Journal:  Sci Transl Med       Date:  2013-07-03       Impact factor: 17.956

Review 4.  Mitochondrial dysfunction and molecular pathways of disease.

Authors:  Steve R Pieczenik; John Neustadt
Journal:  Exp Mol Pathol       Date:  2007-01-18       Impact factor: 3.362

5.  Bisphenol A induces oxidative stress and mitochondrial dysfunction in lymphoblasts from children with autism and unaffected siblings.

Authors:  Kulbir Kaur; Ved Chauhan; Feng Gu; Abha Chauhan
Journal:  Free Radic Biol Med       Date:  2014-08-04       Impact factor: 7.376

6.  Effects of short-term moderate alcohol administration on oxidative stress and nutritional status in healthy males.

Authors:  Giovanni Addolorato; Lorenzo Leggio; Veronica Ojetti; Esmeralda Capristo; Giovanni Gasbarrini; Antonio Gasbarrini
Journal:  Appetite       Date:  2007-06-02       Impact factor: 3.868

Review 7.  Connections between endoplasmic reticulum stress-associated unfolded protein response, mitochondria, and autophagy in arsenic-induced carcinogenesis.

Authors:  Priya Wadgaonkar; Fei Chen
Journal:  Semin Cancer Biol       Date:  2021-04-06       Impact factor: 15.707

Review 8.  Effects of statins on mitochondrial pathways.

Authors:  Hamid Mollazadeh; Erfan Tavana; Giovanni Fanni; Simona Bo; Maciej Banach; Matteo Pirro; Stephan von Haehling; Tannaz Jamialahmadi; Amirhossein Sahebkar
Journal:  J Cachexia Sarcopenia Muscle       Date:  2021-01-29       Impact factor: 12.910

9.  Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance.

Authors:  Soo Lim; Sun Young Ahn; In Chan Song; Myung Hee Chung; Hak Chul Jang; Kyong Soo Park; Ki-Up Lee; Youngmi Kim Pak; Hong Kyu Lee
Journal:  PLoS One       Date:  2009-04-13       Impact factor: 3.240

10.  Mitochondrial toxicity of phthalate esters.

Authors:  R L Melnick; C M Schiller
Journal:  Environ Health Perspect       Date:  1982-11       Impact factor: 9.031

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