Literature DB >> 35698452

Rebound Phenomenon after Nirmatrelvir/Ritonavir Treatment of Coronavirus Disease-2019 in High-Risk Persons.

Nischal Ranganath1, John C O'Horo1,2, Douglas W Challener1, Sidna M Tulledge-Scheitel3, Marsha L Pike4, R Michael O'Brien5, Raymund R Razonable1, Aditya Shah1.   

Abstract

In a cohort of 483 high-risk patients treated with nirmatrelvir/ritonavir for coronavirus disease-2019, two patients (0.4%) required hospitalization by day 30. Four patients (0.8%) experienced rebound of symptoms, which were generally mild, at median of 9 days after treatment, and all resolved without additional COVID-19-directed therapy.
© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Year:  2022        PMID： 35698452      PMCID： PMC9384250          DOI： 10.1093/cid/ciac481

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   20.999


  4 in total

1.  Viral Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Infection in mRNA-Vaccinated Individuals Treated and Not Treated with Nirmatrelvir-Ritonavir.

Authors:  Eric Y Dai; Kannon A Lee; Audrey B Nathanson; Ariana T Leonelli; Brittany A Petros; Taylor Brock-Fisher; Sabrina T Dobbins; Bronwyn L MacInnis; Amelia Capone; Nancy Littlehale; Julie Boucau; Caitlin Marino; Amy K Barczak; Pardis C Sabeti; Michael Springer; Kathryn E Stephenson
Journal:  medRxiv       Date:  2022-08-04

2.  Viral and Symptom Rebound in Untreated COVID-19 Infection.

Authors:  Rinki Deo; Manish C Choudhary; Carlee Moser; Justin Ritz; Eric S Daar; David A Wohl; Alexander L Greninger; Joseph J Eron; Judith S Currier; Michael D Hughes; Davey M Smith; Kara W Chew; Jonathan Z Li
Journal:  medRxiv       Date:  2022-08-02

3.  Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis.

Authors:  Tyler Pitre; Rebecca Van Alstine; Genevieve Chick; Gareth Leung; David Mikhail; Ellen Cusano; Faran Khalid; Dena Zeraatkar
Journal:  CMAJ       Date:  2022-07-25       Impact factor: 16.859

4.  Long Covid, a great imitator of the 21th century.

Authors:  Michel Goldman
Journal:  Front Med (Lausanne)       Date:  2022-09-15
  4 in total

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