| Literature DB >> 35698079 |
Yazhen Bi1,2, Zhaohui Wang3, Saran Feng2, Yan Wang2, Yang Zhao4, Hong Li2, Jingyi Yu2, Qian Liu2, Chuansheng Zhu5,6, Mingzhuo Li7.
Abstract
Entities:
Year: 2022 PMID: 35698079 PMCID: PMC9190074 DOI: 10.1186/s12885-022-09715-w
Source DB: PubMed Journal: BMC Cancer ISSN: 1471-2407 Impact factor: 4.638
Fig. 1Trajectory of PLT counts after induction chemotherapy over time. Each trajectory is represented by a different color. group1: low-stability group, group2: low-level decrease-medium elevation group, group3: low-level decrease-high level elevation group, group4: high-level decrease-medium elevation group
HRs and 95% CIs of trajectories on mortality risk
| Modela | Modelb | Modelc | Modeld | |
|---|---|---|---|---|
| Trajectories groups | ||||
| Group 1 | Reference | Reference | Reference | Reference |
| Group 2 | 0.34 (0.16–0.74)† | 0.32 (0.15–0.68)† | 0.33 (0.14–0.77)‡ | 0.35 (0.15–0.81)‡ |
| Group 3 | 0.29 (0.14–0.59)* | 0.31 (0.15–0.63)† | 0.31 (0.14–0.67)† | 0.30 (0.14–0.66)† |
| Group 4 | 0.36 (0.13–0.99)‡ | 0.35 (0.13–0.89)‡ | 0.41 (0.15–1.09) | 0.27 (0.07–1.09) |
| age | 1.03 (1.01–1.05)† | 1.03 (1.01–1.05)† | 1.03 (1.01–1.05)† | |
| gender | 0.81 (0.46–1.42) | 0.68 (0.35–1.29) | 0.65 (0.33–1.26) | |
| WBC | 1.00 (0.99–1.01) | 1.00 (0.99–1.01) | ||
| Bone marrow blasts | 2.79 (0.64–12.09) | 3.06 (0.68–13.74) | ||
| PLT | 1.00 (0.99–1.01) | |||
HRs hazard ratios, CIs confidence intervals; group 1 to group 4 indicate different trajectories of platelets
aAdjusting for platelet trajectories
bAdjusting for platelet trajectories, age, gender
cAdjusting for platelet trajectories, age, gender, WBC, and bone marrow blasts (bone marrow blasts were damaged, causing 12 to be damaged, leaving 137 people in the model, of whom 87 survived and 50 died)
dAdjusting for platelet trajectories, age, gender, WBC count, bone marrow blasts (bone marrow blasts were damaged, causing 12 to be damaged, leaving 137 people in the model, of whom 87 survived and 50 died.), and PLT
* p<0.001; † p<0.01; ‡ p<0.05