Literature DB >> 35695955

Discharge of newborns with risk factors of severe hyperbilirubinemia: description of a hospital at home-based care monitoring and phototherapy.

Sarah Spyridakis Coquery1, Alexandre Georges1, Anne Cortey2, Corinne Floch3, David Avran1, Edith Gatbois1, Claire Mehler-Jacob1, Matthieu de Stampa4,5.   

Abstract

Neonatal jaundice is common and associated with delay in hospital discharge and risk of neurological sequelae if not treated. The objectives of the study were to report on our experience of the monitoring and treatment of neonatal jaundice in a home care setting and its feasibility and safety for neonates with high risk of severe hyperbilirubinemia. The 2-year study has been led in the greater Paris University Hospital At Home (Assistance Publique-Hôpitaux de Paris). The device of the intervention was the Bilicocoon® Bag, a light-emitting diode sleeping bag worn by the neonate when the total serum bilirubin value exceeds intensive phototherapy threshold, according to the guidelines from the American Academy of Pediatrics. One hundred and thirty-nine neonates had participated in the intervention and 39 (28%) were treated by phototherapy at home, as continuation of inpatient phototherapy or started at home. Seventy-five percent of the sample had more than two risk factors for development of severe hyperbilirubinemia. Twenty five percent of the cohort who received phototherapy at home had lower gestational age (p < 0.014) and had younger age at discharge from maternity (p < 0.09). Median length of stay in hospital at home was 5 days. Two patients needed readmission in conventional hospital (1%) for less than 24 h. In multivariate model, the length of stay decreased with the higher gestational age (p < 0.001) and increased significantly with the older age at discharge, the birth weight < 10th percentile, and a treatment by phototherapy at home.    
Conclusion: Hospital at home, which is a whole strategy using an effective and convenient phototherapy device combined with a specialized medical follow-up, could be an alternative to conventional hospitalization for neonates at high risk of severe jaundice. The maternity discharge is facilitated, the mother-infant bonding can be promoted, and the risk of conventional rehospitalization is minimal, while guaranteeing the safety of this specific care. What is Known: • Managing neonatal jaundice is provided in conventional hospital with phototherapy. • Neonatal jaundice increases the risk of prolonged hospitalization or readmission. What is New: • Phototherapy is feasible in hospital at home for neonates with high risk of severe hyperbilirubinemia. • The care pathway of neonates from conventional hospital to hospital at home is described.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Hospital at home; Hyperbilirubinemia; Neonatal jaundice; Newborn; Phototherapy

Mesh:

Substances:

Year:  2022        PMID: 35695955     DOI: 10.1007/s00431-022-04461-4

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.860


  15 in total

1.  Phototherapy to prevent severe neonatal hyperbilirubinemia in the newborn infant 35 or more weeks of gestation.

Authors:  Vinod K Bhutani
Journal:  Pediatrics       Date:  2011-09-26       Impact factor: 7.124

Review 2.  Neonatal hyperbilirubinemia and early discharge from the maternity ward.

Authors:  Daniele De Luca; Virgilio P Carnielli; Piermichele Paolillo
Journal:  Eur J Pediatr       Date:  2009-03-11       Impact factor: 3.183

3.  Length of stay, jaundice, and hospital readmission.

Authors:  M J Maisels; E Kring
Journal:  Pediatrics       Date:  1998-06       Impact factor: 7.124

Review 4.  Jaundice: Newborn to Age 2 Months.

Authors:  Debra H Pan; Yolanda Rivas
Journal:  Pediatr Rev       Date:  2017-11

Review 5.  Severe neonatal hyperbilirubinemia and kernicterus: are these still problems in the third millennium?

Authors:  Michael Kaplan; Ruben Bromiker; Cathy Hammerman
Journal:  Neonatology       Date:  2011-10-03       Impact factor: 4.035

Review 6.  Kernicterus in term and near-term infants--the specter walks again.

Authors:  T W Hansen
Journal:  Acta Paediatr       Date:  2000-10       Impact factor: 2.299

7.  Predischarge screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy.

Authors:  Vinod K Bhutani; Ann R Stark; Laura C Lazzeroni; Ronald Poland; Glenn R Gourley; Steve Kazmierczak; Linda Meloy; Anthony E Burgos; Judith Y Hall; David K Stevenson
Journal:  J Pediatr       Date:  2012-10-05       Impact factor: 4.406

8.  Imbalance between production and conjugation of bilirubin: a fundamental concept in the mechanism of neonatal jaundice.

Authors:  Michael Kaplan; Maurizio Muraca; Cathy Hammerman; Firmino F Rubaltelli; Maria T Vilei; Hendrik J Vreman; David K Stevenson
Journal:  Pediatrics       Date:  2002-10       Impact factor: 7.124

Review 9.  Hyperbilirubinemia in the 2000s: what should we do next?

Authors:  Gail Ross
Journal:  Am J Perinatol       Date:  2003-11       Impact factor: 1.862

10.  Predictive ability of a predischarge hour-specific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns.

Authors:  V K Bhutani; L Johnson; E M Sivieri
Journal:  Pediatrics       Date:  1999-01       Impact factor: 7.124

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