Literature DB >> 35695892

Ubiquitinating the way to T cell metabolism.

Sarah McPhedran1,2, Julian J Lum1,2.   

Abstract

In this issue, Harris et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202203095) show that phosphofructokinase is a substrate for ubiquitination by Fbxo7, a key protein in the ubiquitination pathway. Their findings point to a new interplay between metabolic enzyme degradation in the regulation of T cells.
© 2022 McPhedran and Lum.

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Year:  2022        PMID: 35695892      PMCID: PMC9198946          DOI: 10.1083/jcb.202206006

Source DB:  PubMed          Journal:  J Cell Biol        ISSN: 0021-9525            Impact factor:   8.077


  6 in total

1.  Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6.

Authors:  Heike Laman; Juan M Funes; Hongtao Ye; Stephen Henderson; Laura Galinanes-Garcia; Eiji Hara; Phillip Knowles; Neil McDonald; Chris Boshoff
Journal:  EMBO J       Date:  2005-08-11       Impact factor: 11.598

Review 2.  The SCF ubiquitin ligase: an extended look.

Authors:  Peter K Jackson; Adam G Eldridge
Journal:  Mol Cell       Date:  2002-05       Impact factor: 17.970

Review 3.  F-box protein interactions with the hallmark pathways in cancer.

Authors:  Suzanne J Randle; Heike Laman
Journal:  Semin Cancer Biol       Date:  2015-09-28       Impact factor: 15.707

Review 4.  Glucose metabolism regulates T cell activation, differentiation, and functions.

Authors:  Clovis S Palmer; Matias Ostrowski; Brad Balderson; Nicole Christian; Suzanne M Crowe
Journal:  Front Immunol       Date:  2015-01-22       Impact factor: 7.561

5.  Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects.

Authors:  Joshua M Dempster; Isabella Boyle; Francisca Vazquez; David E Root; Jesse S Boehm; William C Hahn; Aviad Tsherniak; James M McFarland
Journal:  Genome Biol       Date:  2021-12-20       Impact factor: 13.583

Review 6.  Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins.

Authors:  David E Nelson; Suzanne J Randle; Heike Laman
Journal:  Open Biol       Date:  2013-10-09       Impact factor: 6.411

  6 in total

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