| Literature DB >> 35695737 |
Nicole T Y Ngai1, Christopher C H Yip1, J R Khoo1, Siddharth Sridhar2.
Abstract
Getting vaccinated against SARS-CoV-2 lowers the risk of severe infections. In Hong Kong, two vaccine types are offered: CoronaVac by Sinovac Biotech (Sinovac), and Comirnaty by BioNTech-Fosun Pharma (BioNTech). However, a low vaccine uptake rate is observed. This study primarily aimed to determine the population of medical students who underwent COVID-19 vaccination, and to identify factors associated with their decision on timing and vaccine type. Current medical students from The University of Hong Kong (HKU) were invited to participate in this cross-sectional survey study from 16 September to 31 December 2021. The main outcome measures were the vaccine uptake rate, primary reasons for vaccine-seeking behavior, vaccine hesitancy and vaccine preference, as well as information sources. All questions were of a multiple-choice format, with a free response option for questions pertaining to reason exploration. Overall, 214 medical students participated in the study, with all questionnaires analyzed. Amongst the 98.1% that completed 2 doses, 93.4% selected BioNTech and 6.6% selected Sinovac. Significant associations were observed between year groups and vaccine timing (p = 0.00989). The primary reason to seek vaccination was immunity against COVID-19 (53.5%), while the fear of potential side effects (61.6%) accounted for vaccine hesitancy. The BioNTech vaccine was favored for its higher efficacy against COVID-19 (87.4%). Information sources were mainly from HKU professors (64.6%) and social media (59.9%). The study found a high vaccine uptake rate amongst medical students, contrary to the situation observed in the Hong Kong general population at the time of the study.Entities:
Keywords: COVID-19; Hong Kong; attitudes; behaviour; medical students; vaccine
Mesh:
Substances:
Year: 2022 PMID: 35695737 PMCID: PMC9481110 DOI: 10.1080/21645515.2022.2074761
Source DB: PubMed Journal: Hum Vaccin Immunother ISSN: 2164-5515 Impact factor: 4.526
Table of demographics and vaccination status.
| Demographics | Number (%) of Participants |
|---|---|
| Gender | 111 (51.9%) |
| Year Group | 15 (7%) |
| Number of doses: | 210 (98.1%) |
| BioNTech | 199 (93.4%) |
| Sinovac | 14 (6.6%) |
Figure 1.Vaccine uptake rate amongst HKU medical students against total number of COVID-19 cases in Hong Kong.
Table of underlying reasons associated with vaccine hesitancy.
| Reason for Vaccine Hesitancy | Number (%) of Participants |
|---|---|
| Fear of potential serious side effects | 45 (61.6%) |
| Waiting to assess outcomes of other people who have received the vaccine first | 40 (54.8%) |
| Busy work/study schedule | 29 (39.7%) |
| Lack of urgency due to relatively stable COVID19 situation in Hong Kong | 21 (28.8%) |
| Familial influence to delay vaccination | 19 (26.0%) |
| Lack of trust in vaccine manufacturers/public health agencies | 9 (12.3%) |
| Free responses | 1 (1.4%) |
Table of underlying reasons associated with BioNtech selection.
| Number (%) of Participants | ||
|---|---|---|
| Reason for BioNTech selection | Primary reason | Secondary reason |
| Higher vaccine efficacy against COVID19 | 174 (87.4%) | 33 (17.9%) |
| Vaccine passport | 8 (4%) | 131 (71.2%) |
| Offered at the HKU Community Vaccination Center at Ap Lei Chau | 7 (3.5%) | 102 (55.4%) |
| Fewer reported side effects | 7 (3.5%) | 41 (22.3%) |
| Preference for mRNA technology | 0 (0%) | 59 (32.1%) |
| Free response | 2 (1%) | 2 (1%) |
Table of underlying reasons associated with Sinovac selection.
| Number (%) of Participants | ||
|---|---|---|
| Reason for Sinovac selection | Primary reason | Secondary reason |
| Preference for inactivated virus technology | 6 (42.9%) | 5 (55.6%) |
| Fewer reported side effects | 5 (35.7%) | 4 (44.4%) |
| Vaccine passport | 1 (7.1%) | 5 (55.6%) |
| Offered at Community Vaccine Centers | 1 (7.1%) | 3 (33.3%) |
| Free response | 1 (7.1%) | - |
Table of underlying reasons associated with vaccination-seeking behavior.
| Number (%) of Participants | ||
|---|---|---|
| Reason to get vaccinated | Primary reason | Secondary reason |
| Immunity against COVID19 | 114 (53.5%) | 77 (38.1%) |
| Hospital Authority’s arrangement to exclude vaccinated students from mandatory COVID tests in clinical areas | 53 (24.9%) | 86 (42.6%) |
| Fear of infecting other family members/friends/patients | 12 (5.7%) | 118 (58.4%) |
| Vaccine Passport | 9 (4.2%) | 108 (53.5%) |
| Duty of a medical student | 9 (4.2%) | 121 (59.9%) |
| Relaxed social distancing measures for fully vaccinated | 5 (2.3%) | 103 (51%) |
| Contributing to herd immunity | 4 (1.9%) | 125 (61.9%) |
| Attraction to return to normal life | 4 (1.9%) | 113 (55.9%) |
| Free responses | 1 (0.5%) | - |
Figure 2.Information source.