Literature DB >> 3569495

Interferon-beta can induce the production of plasminogen activator by cultured human cancer cells.

M Karai, M Namba.   

Abstract

Three cultured human cell lines, renal cancer cells (ACHN), bladder cancer cells (EJ), and fibroblasts transformed in culture by Co-60 gamma rays (KMST-6), when treated with interferon-beta, produced 1.5 to 4 times as much plasminogen activator as the untreated control cultures. This enhanced production of PA was inhibited by cycloheximide or actinomycin D.

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Year:  1987        PMID： 3569495     DOI： 10.1007/bf01940443

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  24 in total

1.  Virus interference. I. The interferon.

Authors:  A ISAACS; J LINDENMANN
Journal:  Proc R Soc Lond B Biol Sci       Date:  1957-09-12

2.  Stimulation of in vitro immunoglobulin production by interferon-alpha.

Authors:  R H Neubauer; L Goldstein; H Rabin; N Stebbing
Journal:  J Immunol       Date:  1985-01       Impact factor: 5.422

3.  Differential effects of interferon on the expression of H-2K, H-2D, and Ia antigens on mouse lymphocytes.

Authors:  F Vignaux; I Gresser
Journal:  J Immunol       Date:  1977-02       Impact factor: 5.422

Review 4.  Mechanism of interferon action: progress toward its understanding.

Authors:  G C Sen
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1982

Review 5.  Tumor invasion and host extracellular matrix.

Authors:  B U Pauli; D E Schwartz; E J Thonar; K E Kuettner
Journal:  Cancer Metastasis Rev       Date:  1983       Impact factor: 9.264

6.  Antibodies to plasminogen activator inhibit human tumor metastasis.

Authors:  L Ossowski; E Reich
Journal:  Cell       Date:  1983-12       Impact factor: 41.582

7.  Fibrinolytic activity in a human fibrosarcoma cell line and evidence for the induction of plasminogen activator secretion during tumor formation.

Authors:  P A Jones; W E Laug; W F Benedict
Journal:  Cell       Date:  1975-10       Impact factor: 41.582

8.  Comparison of in vitro and in vivo modulation of myelopoiesis by biological response modifiers.

Authors:  E Schlick; K Hartung; M A Chirigos
Journal:  Cancer Immunol Immunother       Date:  1984       Impact factor: 6.968

9.  Induction of HLA class-II antigen expression on human carcinoma cell lines by IFN-Gamma.

Authors:  R Schwartz; F Momburg; G Moldenhauer; B Dörken; V Schirrmacher
Journal:  Int J Cancer       Date:  1985-02-15       Impact factor: 7.396

10.  Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity.

Authors:  P S Steeg; R N Moore; H M Johnson; J J Oppenheim
Journal:  J Exp Med       Date:  1982-12-01       Impact factor: 14.307
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