| Literature DB >> 35692619 |
Gabriele Sachs1, Gloria Bannick2,3, Eva I J Maihofer2, Martin Voracek3, Scot E Purdon4, Andreas Erfurth1,2.
Abstract
Background: Psychiatric disorders, especially schizophrenia, are characterised by cognitive impairment. The rapid detection of cognitive dysfunction - also in the course of the disease - is of great importance. The Screen for Cognitive Impairment in Psychiatry (SCIP) was developed to provide screening of psychiatric patients in clinical practice and is available in several languages. Prior psychometric investigations into the dimensionality of the SCIP have produced two different models: a one-factor model assumes that the five subscales of the SCIP load together, whereas an alternative model suggests that the subscales load on two factors, namely verbal memory and processing speed. We carried out a confirmatory factor analysis of the German version of the SCIP (SCIP-G).Entities:
Keywords: Confirmatory factor analysis; Psychometrics; Schizophrenia; Screen for Cognitive Impairment in Psychiatry (SCIP); Structural equation modeling
Year: 2022 PMID: 35692619 PMCID: PMC9178470 DOI: 10.1016/j.scog.2022.100259
Source DB: PubMed Journal: Schizophr Res Cogn ISSN: 2215-0013
Demographic variables.
| N | 323 | |
|---|---|---|
| Age | ||
| Mean (± SD) | 37.72 (13.01) | |
| Range | 18–64 | |
| Median | 37 | |
| Gender (%) | ||
| Female | 179 (55.4) | |
| Male | 144 (44.6) | |
| Diagnostic group (%) | ||
| F2 (schizophrenia, schizotypal and delusional disorders) | 119 (36.8) | |
| F30/31 (bipolar disorder) | 69 (21.4) | |
| F32/33 (depression) | 126 (39.0) | |
| Missing | 9 (2.8) | |
N represents sample size, SD = standard deviation, the diagnoses were made according to the ICD-10 Criteria for Research (World Health Organization, 2011).
Means, standard deviations, and correlations with confidence intervals
| Variable | M | SD | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|---|---|
| 1. SCIP-G | 69.91 | 12.53 | |||||
| 2. VLT-I | 22.68 | 4.13 | 0.81 | ||||
| 3. WMT | 18.72 | 3.68 | 0.74 | 0.52 | |||
| 4. VFT | 12.11 | 4.28 | 0.69 | 0.36 | |||
| 5. VLT-D | 7.15 | 2.33 | 0.69 | 0.40 | 0.23 | ||
| 6. PST | 9.34 | 3.01 | 0.66 | 0.37 | 0.36 | 0.41 | 0.35 |
M = Mean, SD = Standard Deviation. VLT-I = Verbal Learning Test-Immediate, WMT = Working Memory Test, VFT = Verbal Fluency Test, VLT-D = Verbal Learning Test-Delayed, PST = Psychomotor Speed Test. 95% confidence interval for correlations in brackets. Values in bold refer to the correlations between the VLT-I-VLT-D and VFT-WMT subtests addressed in Hypotheses 3 and 4 respectively (see main text).
Pearson correlations.
⁎p < 0.05..
p < 0.01.
Factor loadings for the one-factor model and the two-factor model.
| Variable | M1 | M2 | ||
|---|---|---|---|---|
| F1 | F2 | |||
| VLT-I | 0.075 | 0.718 | ||
| WMT | 0.588 | 0.722 | ||
| VFT | 0.628 | 0.636 | ||
| VLT-D | 0.131 | 0.560 | ||
| PST | 0.631 | 0.640 | ||
| Correlated error term VLT-I-VLT-D | 0.673 | 0.520 |
N = 323. M1 = one-factor model, M2 = two-factor model. F1 = memory, F2 = processing speed (Pino et al., 2006). VLT-I = Verbal Learning Test-Immediate, WMT = Working Memory Test, VFT = Verbal Fluency Test, VLT-D = Verbal Learning Test-Delayed, PST = Psychomotor Speed Test. Calculations utilised the robust maximum likelihood estimation method; factor intercorrelation between M1 and M2 is r = 0.797 (p < 0.001); values shown are fully standardised factor loadings with p < 0.001.
Goodness-of-fit statistics.
| Fit measures | One-factor model (M1) | Two-factor model (M2) |
|---|---|---|
| χ2 | 109.517 | 6.730 |
| χ2/df | 21.9 | 2.24 |
| p value | <0.001 | 0.081 |
| RMSEA | 0.254 | 0.062 |
| CFI | 0.754 | 0.991 |
| NFI | 0.748 | 0.985 |
| SRMR | 0.207 | 0.021 |
| AIC | 12,928.049 | 12,825.843 |
N = 323; p < 0.05; df(M1) = 5; df(M2) = 3.
For model evaluation, the model-fit measures chi-squared test (χ2 value), Root Mean Square Error of Approximation (RMSEA), Comparative Fit Index (CFI), Normed Fit Index (NFI), Standardised Root Mean Square Residual (SRMR), and Akaike Information Criterion (AIC) were used.
Goodness-of-fit statistics of the separated groups for the one-factor-model.
| Fit measures | Psychotic sample | Depressed sample |
|---|---|---|
| χ2 | 43.657 | 56.610 |
| χ2/df | 8.73 | 11.32 |
| p value | <0.001 | <0.001 |
| RMSEA | 0.258 | 0.227 |
| CFI | 0.770 | 0.763 |
| NFI | 0.751 | 0.781 |
| SRMR | 0.221 | 0.180 |
| AIC | 4690.325 | 7924.766 |
N(psychotic) = 116; p < 0.05; df = 5; N(depressed) = 200; p < 0.05; df = 5. For model evaluation, the model-fit measures chi-squared test (χ2 value), Root Mean Square Error of Approximation (RMSEA), Comparative Fit Index (CFI), Normed Fit Index (NFI), Standardised Root Mean Square Residual (SRMR), and Akaike Information Criterion (AIC) were used.
Factor loadings for the two-factor model with separated groups psychotic vs. depressed.
| Variable | Psychotic sample | Depressed sample | ||||
|---|---|---|---|---|---|---|
| F1 | F2 | F1 | F2 | |||
| VLT-I | 0.756 | 0.666 | ||||
| WMT | 0.705 | 0.691 | ||||
| VFT | 0.578 | 0.624 | ||||
| VLT-D | 0.611 | 0.500 | ||||
| PST | 0.809 | 0.547 | ||||
| Correlated error term VLT-I-VLT-D | 0.468 | 0.533 |
N(psychotic) = 116; N(depressed) = 200. F1 = memory, F2 = processing speed (Pino et al., 2006). VLT-I = Verbal Learning Test-Immediate, WMT = Working Memory Test, VFT = Verbal Fluency Test, VLT-D = Verbal Learning Test-Delayed, PST = Psychomotor Speed Test. Calculations utilised the robust maximum likelihood estimation method; factor intercorrelation between F1 and F2 (psychotic sample) is r = 0.731 (p < 0.001); factor intercorrelation between F1 and F2 (depressed sample) is r = 0.842 (p < 0.001); values shown are fully standardised factor loadings with p < 0.001.
Goodness-of-fit statistics of the separated groups for the two-factor-model.
| Fit measures | Psychotic sample | Depressed sample |
|---|---|---|
| χ2 | 2.785 | 6.118 |
| χ2/df | 0.928 | 2.039 |
| p value | 0.426 | 0.106 |
| RMSEA | 0.000 | 0.072 |
| CFI | 1.000 | 0.986 |
| NFI | 0.985 | 0.976 |
| SRMR | 0.025 | 0.025 |
| AIC | 4650.596 | 7879.184 |
N(psychotic) = 116; p < 0.05; df = 3; N(depressed) = 200; p < 0.05; df = 3. For model evaluation, the model-fit measures chi-squared test (χ2 value), Root Mean Square Error of Approximation (RMSEA), Comparative Fit Index (CFI), Normed Fit Index (NFI), Standardised Root Mean Square Residual (SRMR), and Akaike Information Criterion (AIC) were used.
Chi-square difference test.
| df | AIC | BIC | Chi-square | Chi-square difference | Probability (>Chi-square) | |
|---|---|---|---|---|---|---|
| Two-factor-model | 3 | 12,826 | 12,871 | 6.8995 | ||
| One-factor-model | 6 | 13,076 | 13,110 | 262.6651 | 183.52 | <2.2e-16*** |
| Baseline model | 10 | 13,286 | 13,286 | 481.1519 | 228.78 | <2.2e-16*** |
df: Degrees of freedom. BIC: Bayesian Information Criterion.
Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1