Literature DB >> 3568934

Comparison of effects of ingested medium- and long-chain triglyceride on gallbladder volume and release of cholecystokinin and other gut peptides.

P E Isaacs, S Ladas, I C Forgacs, R H Dowling, S V Ellam, T E Adrian, S R Bloom.   

Abstract

In a double-blind, crossover study of the effect of ingested medium-chain triglyceride (MCT) and long-chain triglyceride (LCT) in six normal subjects, the gallbladder did not contract after ingestion of MCT but instead had significantly increased in volume at 2 hr after the meal. Plasma cholecystokinin (CCK) increased after the MCT meal, but gastrin, motilin, pancreatic polypeptide (PP), and GIP were unaffected. The long-chain triglyceride meal evoked a brisk and sustained gallbladder contraction, higher levels of CCK, and a significant increase in plasma PP and GIP levels.

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Year:  1987        PMID： 3568934     DOI： 10.1007/bf01296030

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN： 0163-2116            Impact factor:   3.199


  18 in total

1.  Release of immunoreactive gastric inhibitory polypeptide (IR-GIP) by oral ingestion of food substances.

Authors:  I G Cleator; R H Gourlay
Journal:  Am J Surg       Date:  1975-08       Impact factor: 2.565

2.  Measurement of human plasma motilin.

Authors:  S R Bloom; P Mitznegg; M G Bryant
Journal:  Scand J Gastroenterol Suppl       Date:  1976

3.  Absorption of medium-chain triglycerides in animals with pancreatic atrophy.

Authors:  V Valdivieso
Journal:  Am J Dig Dis       Date:  1972-02

4.  Immunochemical studies on cholecystokinin. I. Development of sequence-specific radioimmunoassays for porcine triacontatriapeptide cholecystokinin.

Authors:  J F Rehfeld
Journal:  J Biol Chem       Date:  1978-06-10       Impact factor: 5.157

5.  Comparison of gallbladder contractions induced by motilin and cholecystokinin in dogs.

Authors:  I Takahashi; T Suzuki; I Aizawa; Z Itoh
Journal:  Gastroenterology       Date:  1982-03       Impact factor: 22.682

6.  A critical evaluation of real-time ultrasonography for the study of gallbladder volume and contraction.

Authors:  G T Everson; D Z Braverman; M L Johnson; F Kern
Journal:  Gastroenterology       Date:  1980-07       Impact factor: 22.682

7.  Distribution and release of human pancreatic polypeptide.

Authors:  T E Adrian; S R Bloom; M G Bryant; J M Polak; P H Heitz; A J Barnes
Journal:  Gut       Date:  1976-12       Impact factor: 23.059

8.  Bile acid output and the interdigestive migrating motor complex in normals and in cholecystectomy patients.

Authors:  T L Peeters; G Vantrappen; J Janssens
Journal:  Gastroenterology       Date:  1980-10       Impact factor: 22.682

9.  Release of motilin by oral and intravenous nutrients in man.

Authors:  N D Christofides; S R Bloom; H S Besterman; T E Adrian; M A Ghatei
Journal:  Gut       Date:  1979-02       Impact factor: 23.059

10.  Neural regulation of pancreatic hormone secretion by the C-terminal tetrapeptide of CCK.

Authors:  J F Rehfeld; L I Larsson; N R Goltermann; T W Schwartz; J J Holst; S L Jensen; J S Morley
Journal:  Nature       Date:  1980-03-06       Impact factor: 49.962
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  13 in total

Review 1.  Visceral perception: sensory transduction in visceral afferents and nutrients.

Authors:  H E Raybould
Journal:  Gut       Date:  2002-07       Impact factor: 23.059

2.  Apolipoprotein A-IV is involved in detection of lipid in the rat intestine.

Authors:  K L Whited; D Lu; P Tso; K C Kent Lloyd; H E Raybould
Journal:  J Physiol       Date:  2005-10-20       Impact factor: 5.182

3.  An exaggerated sensory component of the gastrocolonic response in patients with irritable bowel syndrome.

Authors:  M Simrén; H Abrahamsson; E S Björnsson
Journal:  Gut       Date:  2001-01       Impact factor: 23.059

4.  Fatty acid-induced cholecystokinin secretion and changes in intracellular Ca2+ in two enteroendocrine cell lines, STC-1 and GLUTag.

Authors:  S S Sidhu; D G Thompson; G Warhurst; R M Case; R S Benson
Journal:  J Physiol       Date:  2000-10-01       Impact factor: 5.182

5.  Sensations induced by medium and long chain triglycerides: role of gastric tone and hormones.

Authors:  R Barbera; M Peracchi; F Brighenti; B Cesana; P A Bianchi; G Basilisco
Journal:  Gut       Date:  2000-01       Impact factor: 23.059

6.  Effects of medium-chain and long-chain triglycerides on antroduodenal motility and small bowel transit time in man.

Authors:  M Verkijk; J Vecht; H A Gielkens; C B Lamers; A A Masclee
Journal:  Dig Dis Sci       Date:  1997-09       Impact factor: 3.199

Review 7.  Recent findings in the study of postprandial lipemia.

Authors:  E J Parks
Journal:  Curr Atheroscler Rep       Date:  2001-11       Impact factor: 5.113

8.  Effects of oleic acid and endogenous bile on duodenal secretion of somatostatin in man.

Authors:  O Olsen; J J Holst; O B Schaffalitzky De Muckadell
Journal:  Dig Dis Sci       Date:  1992-07       Impact factor: 3.199

9.  Oral administration of loxiglumide (CCK antagonist) inhibits postprandial gallbladder contraction without affecting gastric emptying.

Authors:  E Corazziari; R Ricci; D Biliotti; I Bontempo; A De Medici; N Pallotta; A Torsoli
Journal:  Dig Dis Sci       Date:  1990-01       Impact factor: 3.199

10.  Fatty acids stimulate cholecystokinin secretion via an acyl chain length-specific, Ca2+-dependent mechanism in the enteroendocrine cell line STC-1.

Authors:  J T McLaughlin; R B Lomax; L Hall; G J Dockray; D G Thompson; G Warhurst
Journal:  J Physiol       Date:  1998-11-15       Impact factor: 5.182
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