| Literature DB >> 35689235 |
Mohammed Akhtar1, Sameera Rashid2, Issam A Al-Bozom1.
Abstract
Entities:
Year: 2022 PMID: 35689235 PMCID: PMC9188219 DOI: 10.1186/s13000-022-01229-0
Source DB: PubMed Journal: Diagn Pathol ISSN: 1746-1596 Impact factor: 3.196
Fig. 11A Case of metastatic pulmonary adenocarcinoma to the liver. B Immunohistochemical staining for tumor cells, moderate to intense staining (2 + − 3+) for PD-L1 TPS: 90 (DAKO 22C3 antibody)
Fig. 12A Case of buccal mucosa squamous cell carcinoma. B Immunohistochemical staining for PD-L1 revealing staining of tumor cells (right side of the figure) and tumor immune cells (left side of the figure). CPS: 90 (DAKO 22C3 antibody)
Fig. 15A diagram depicting expression of PD-L1 positive tumor infiltrating immune cells (marked by red border) in an area of tumor cells (marked by black dotted line). The proportion of tumor area occupied by PD-L1-positive immune cells of any intensity determines the immune cell (IC) score
Fig. 13A Case of poorly differentiated gastric adenocarcinoma. B Immunohistochemical staining of the tumor showing staining of tumor immune cells while tumor cells are predominantly negative. CPS: 20. (DAKO 22C3 antibody)
Fig. 14A Case of moderately differentiated gastric adenocarcinoma. B Immunohistochemical staining of the tumor in which only tumor cells are positive for PD-L1; while tumor immune cells are negative. CPS: 80. (DAKO 22C3 antibody)