Literature DB >> 35684585

Correction: Döring et al. Discovery of Novel Symmetrical 1,4-Dihydropyridines as Inhibitors of Multidrug-Resistant Protein (MRP4) Efflux Pump for Anticancer Therapy. Molecules 2021, 26, 18.

Henry Döring1, David Kreutzer1, Christoph Ritter2, Andreas Hilgeroth1.   

Abstract

The authors would like to correct an error made through no fault of their own in the title paper [...].

Entities:  

Year:  2022        PMID: 35684585      PMCID: PMC9181869          DOI: 10.3390/molecules27113575

Source DB:  PubMed          Journal:  Molecules        ISSN: 1420-3049            Impact factor:   4.927


The authors would like to correct an error made through no fault of their own in the title paper [1]. The error is related to the FAR values in Table 1. In the earlier published version, the FAR values of compounds 15–21 were wrongly printed. So, they had to be corrected, from 1.19 to 1.12 for 15, 1.55 to 1.19 for 16, 0.95 to 1.55 for 17, 1.22 to 0.95 for 18, 0.98 to 1.22 for 19, 1.30 to 0.98 for 20 and 0.82 to 1.30 for 21. We provide below the corrected Table 1. The change has no influence on the reported results. The original article has been updated. The authors would like to apologize for any inconvenience caused to the readers by this change.
Table 1

MRP4 inhibition data of target compounds 4–21 with varied substitution patterns expressed as FAR values.

CompoundR1R2R3R4 FAR
Value [a]
4 CF3HCF3H1.28
5 CF3HOMeH1.21
6 CF3HHOMe1.11
7 CF3HOMeOMe1.10
8 HCF3OMeH1.28
9 HCF3HOMe1.11
10 HCF3OMeOMe1.26
11 FFOMeH1.43
12 FFHOMe1.40
13 FFOMeOMe1.23
14 FHOMeOMe1.21
15 HFOMeOMe1.12
16 CF3OMeCF3H1.19
17 CF3OMeOMeH1.55
18 CF3OMeHOMe0.95
19 CF3OMeOMeOMe1.22
20 OMeOMeCF3H0.98
21 OBnOBnCF3H1.30

[a] Fluorescence activity ratio as mean of three determinations.

  1 in total

1.  Discovery of Novel Symmetrical 1,4-Dihydropyridines as Inhibitors of Multidrug-Resistant Protein (MRP4) Efflux Pump for Anticancer Therapy.

Authors:  Henry Döring; David Kreutzer; Christoph Ritter; Andreas Hilgeroth
Journal:  Molecules       Date:  2020-12-22       Impact factor: 4.411

  1 in total

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