Literature DB >> 35679719

Exploring the plant-derived bioactive substances as antidiabetic agent: An extensive review.

Md Mominur Rahman1, Puja Sutro Dhar1, Fazilatunnesa Anika1, Limon Ahmed1, Md Rezaul Islam1, Nazneen Ahmeda Sultana1, Simona Cavalu2, Ovidiu Pop3, Abdur Rauf4.   

Abstract

Diabetes mellitus (DM) is a metabolic syndrome. Diabetes has become more common in recent years. Chemically generated drugs are used to lessen the effects of DM and its following repercussions due to unpleasant side effects such as weight gain, gastrointestinal issues, and heart failure. On the other hand, medicinal plants could be a good source of anti-diabetic medications. This article aims to determine any plant matrix's positive potential. Food restriction, physical activity, and the use of antidiabetic plant-derived chemicals are all being promoted as effective ways to manage diabetes because they are less expensive and have fewer or no side effects. This review focuses on antidiabetic plants, along with their bioactive constituent, chemically characterization, and plant-based diets for diabetes management. There is minimal scientific data about the mechanism of action of the plant-based product has been found. The purpose of this article is to highlight anti-diabetic plants and plant-derived bioactive compounds that have anti-diabetic properties. It also provides researchers with data that may be used to build future strategies, such as identifying promising bioactive molecules to make diabetes management easier.
Copyright © 2022 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

Entities:  

Keywords:  Diabetes mellitus; Flavone; Hyperglycemia; Monoterpenes; Polyphenolics

Mesh:

Substances:

Year:  2022        PMID: 35679719     DOI: 10.1016/j.biopha.2022.113217

Source DB:  PubMed          Journal:  Biomed Pharmacother        ISSN: 0753-3322            Impact factor:   6.529


  11 in total

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Review 7.  Exploring the recent trends in perturbing the cellular signaling pathways in cancer by natural products.

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Journal:  Front Pharmacol       Date:  2022-09-08       Impact factor: 5.988

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Journal:  Evid Based Complement Alternat Med       Date:  2022-09-08       Impact factor: 2.650

Review 10.  Insights into the Promising Prospect of G Protein and GPCR-Mediated Signaling in Neuropathophysiology and Its Therapeutic Regulation.

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Journal:  Oxid Med Cell Longev       Date:  2022-09-21       Impact factor: 7.310

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