Literature DB >> 35678842

Novel molded antibiotic cement spacer: is it better than handmade cement spacer for treatment of chronically infected total hip arthroplasty?

Piya Pinsornsak1, Ta Niruktisarn1, Potsawat Surabotsopon1, Krit Boontanapibul2.   

Abstract

PURPOSE: A handmade antibiotic cement spacer is the easiest method for producing a spacer for treating chronic periprosthetic joint infection after total hip arthroplasty (THA). However, a molded spacer offers more head and stem sizes to match the patient's anatomy. The purpose of this study was to evaluate the functional outcomes and complications between handmade and molded spacers.
METHODS: This retrospective case note study compared the functional results, re-infection rate, and spacer related complications after the first stage and second stage exchange arthroplasty between a handmade spacer and a novel molded cement spacer with three sizes of femoral head (45, 50, and 55 mm) and two stem sizes (small, large).
RESULTS: Fifteen chronically infected THA patients were identified: nine handmade and 6 molded spacers. The modified Harris Hip Score showed no inter-group differences pre-operatively and after first stage and second stage exchange arthroplasty. The erythrocyte sedimentary rates and C-reactive protein concentrations were similar at all time points, and there were no re-infections. The molded spacer group showed lower post-operative complications with no spacer fractures, spacer dislocations, and periprosthetic fractures, but two had spacer subsidence. The handmade spacer had two spacer fractures, one spacer dislocation with a periprosthetic femoral fracture, and four cases of spacer subsidence.
CONCLUSION: Our small study showed no differences in functional outcomes and no re-infections in either group, but higher spacer-related complications occurred in the handmade spacer group. These data suggest molded spacers are better than handmade spacers.
© 2022. The Author(s) under exclusive licence to SICOT aisbl.

Entities:  

Keywords:  Antibiotic; Cement spacer; Handmade; Hip arthroplasty; Molded; Periprosthetic joint infection

Mesh:

Substances:

Year:  2022        PMID: 35678842     DOI: 10.1007/s00264-022-05456-4

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.479


  12 in total

1.  Use of telephone interviews to follow up patients after total hip replacement.

Authors:  Sanjeev Sharma; Ravi Shah; Kingsley Paul Draviraj; M S Bhamra
Journal:  J Telemed Telecare       Date:  2005       Impact factor: 6.184

2.  Hip instability in 2-stage reimplantation without an articulating spacer.

Authors:  Thomas K Fehring; Susan Odum; Stephen Struble; Keith Fehring; William L Griffin; J Bohannon Mason
Journal:  J Arthroplasty       Date:  2007-07-26       Impact factor: 4.757

Review 3.  Infection after primary total hip arthroplasty.

Authors:  Bennie Lindeque; Zach Hartman; Andriy Noshchenko; Margaret Cruse
Journal:  Orthopedics       Date:  2014-04       Impact factor: 1.390

Review 4.  Similar rate of infection eradication for functional articulating, prefabricated and custom-made spacers in 2-stage revision of the infected total hip: a literature review.

Authors:  Ewout S Veltman; Dirk Jan F Moojen; Mathias Glehr; Rudolf W Poolman
Journal:  Hip Int       Date:  2016-06-29       Impact factor: 2.135

5.  Custom-made, antibiotic-loaded, acrylic cement spacers using a dental silicone template for treatment of infected hip prostheses.

Authors:  Tadahiko Ohtsuru; Yuji Morita; Yasuaki Murata; Yutaro Munakata; Masafumi Itoh; Yoshiharu Kato; Ken Okazaki
Journal:  Eur J Orthop Surg Traumatol       Date:  2018-01-13

6.  The effect of endoskeleton on antibiotic impregnated cement spacer for treating deep hip infection.

Authors:  Kuo-Ti Peng; Liang-Tseng Kuo; Wei-Hsiu Hsu; Tsan-Wen Huang; Yao-Hung Tsai
Journal:  BMC Musculoskelet Disord       Date:  2011-01-13       Impact factor: 2.362

Review 7.  Prosthetic joint infections.

Authors:  Antonia F Chen; Snir Heller; Javad Parvizi
Journal:  Surg Clin North Am       Date:  2014-09-30       Impact factor: 2.741

8.  Two stage revision hip arthroplasty in periprosthetic joint infection. Comparison study: with or without the use of a spacer.

Authors:  Dariusz Marczak; Marek Synder; Marcin Sibiński; Michał Polguj; Julian Dudka; Jacek Kowalczewski
Journal:  Int Orthop       Date:  2017-05-18       Impact factor: 3.075

9.  Spacer Design Options and Consideration for Periprosthetic Joint Infection.

Authors:  Scott M Sporer
Journal:  J Arthroplasty       Date:  2020-03       Impact factor: 4.757

10.  Are Preformed Articulating Spacers Superior To Surgeon-Made Articulating Spacers in the Treatment Of PJI in THA? A Literature Review.

Authors:  Mustafa Citak; Bassam A Masri; Bryan Springer; Jean-Noel Argenson; Daniel O Kendoff
Journal:  Open Orthop J       Date:  2015-07-31
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