| Literature DB >> 35676079 |
Sabine J A van der Graaff1, Susanne M Eijgenraam1, Duncan E Meuffels1, Eline M van Es1, Jan A N Verhaar1, Dirk Jan Hofstee2, Kiem Gie Auw Yang3, Julia C A Noorduyn4, Ewoud R A van Arkel5, Igor C J B van den Brand6, Rob P A Janssen7,8, Wai-Yan Liu7,9, Sita M A Bierma-Zeinstra1,10, Max Reijman11.
Abstract
OBJECTIVE: To compare outcomes from arthroscopic partial meniscectomy versus physical therapy in young patients with traumatic meniscal tears.Entities:
Keywords: Meniscus; Randomized Controlled Trial
Year: 2022 PMID: 35676079 PMCID: PMC9304087 DOI: 10.1136/bjsports-2021-105059
Source DB: PubMed Journal: Br J Sports Med ISSN: 0306-3674 Impact factor: 18.473
Figure 1Flowchart. (A) minus 2 baseline questionnaires, 1 because of study withdrawal and 1 was incomplete. (B) minus 1 study withdrawal, who had no available data.
Baseline characteristics
| Arthroscopic partial meniscectomy | Physical therapy | |
| Age at inclusion, years | 34.1 (8.6) | 35.6 (7.5) |
| Male sex, n (%) | 37 (77) | 38 (75) |
| BMI (kg/m2) | 25.5 (4.2) | 26.1 (4.6) |
| Tegner preinjury* | 6.5 (2.2) | 6.4 (2.0) |
| Time between trauma and inclusion, days (median (IQR)) | 88 (48–150) | 91 (58–149) |
| IKDC score† | 46 (16) | 47 (18) |
| KOOS score‡ | ||
| Pain | 54 (20) | 60 (21) |
| Symptoms | 56 (20) | 63 (18) |
| ADL | 61 (22) | 69 (22) |
| Sport | 30 (25) | 35 (29) |
| QoL | 34 (18) | 36 (18) |
| NRS-pain rest§ | 3.9 (2.5) | 2.9 (2.8) |
| NRS-pain activity§ | 6.6 (2.4) | 6.2 (2.4) |
| Lysholm score¶ | 67 (18) | 70 (18) |
| WOMET score** | 38 (18) | 43 (19) |
| Meniscus injured during, n (%) | ||
| Sport | 27 (56) | 27 (53) |
| Daily activities | 5 (10) | 11 (22) |
| Work | 10 (21) | 8 (16) |
| Other | 5 (10) | 5 (10) |
| Meniscal tear baseline MRI, n (%) | ||
| Medial meniscus | 31 (65) | 35 (69) |
| Lateral meniscus | 16 (33) | 14 (27) |
| Medial+lateral meniscus | 1 (2) | 2 (4) |
Data are presented as mean with SD in brackets unless otherwise reported.
Some values of the arthroscopic partial meniscectomy group are known for 47 patients instead of 48.
*The Tegner scores ranges from 0 to 10, with higher scores indicating a higher activity level.
†The IKDC score ranges from 0 to 100, with higher scores indicating less symptoms and a higher patient’s perception of knee function and ability to participate in sports activities.
‡The Knee Osteoarthritis Outcome Score ranges from 0 to 100, with higher scores indicating less pain and knee symptoms, less problems with ADL and sport and a better QoL.
§The NRS for pain ranges from 0 to 10, with higher scores indicating more pain.
¶The Lysholm score ranges from 0 to 100, with higher scores indicating less knee symptoms and higher levels of functioning.
**The WOMET normalised score ranges from 0 to 100, with higher scores indicating a higher health-related quality of life.
ADL, activities of daily living; IKDC, International Knee Documentation Committee; KOOS, Knee Injury and Osteoarthritis Outcome Score; NRS, Numeric Rating Scale; QoL, quality of life; WOMET, Western Ontario Meniscal Evaluation Tool.
Figure 2Estimated IKDC scorea for as randomised analyses per measurement period. (A) 3, 6, 9 and 12 months: adjusted for surgeon, 24 months: adjusted for baseline IKDC, randomisation and surgeon. Error bars represent 95% CI. Table: 95% CI in brackets. IKDC score ranges from 0 to 100, with higher scores indicating less symptoms and a higher patient’s perception of knee function and ability to participate in sports activities. IKDC, International Knee Documentation Committee.
Secondary outcomes* for as randomised analyses 24-month follow-up
| Arthroscopic partial meniscectomy | Physical therapy | Between group difference | |
| KOOS† | |||
| Pain | 86 (79 to 92) | 84 (77 to 90) | 1.9 (−5.7 to 9.6) |
| Symptoms | 82 (75 to 88) | 81 (75 to 88) | 0.5 (−6.6 to 7.5) |
| ADL | 92 (87 to 98) | 89 (84 to 94) | 2.8 (−3.3 to 8.9) |
| Sport | 70 (61 to 80) | 69 (60 to 79) | 0.8 (−12.5 to 14.0) |
| QoL | 67 (59 to 75) | 66 (58 to 74) | 1.4 (−9.3 to 12.0) |
| NRS-pain rest‡ | 1.2 (0.4 to 1.9) | 1.2 (0.5 to 2.0) | −0.1 (−0.8 to 0.7) |
| NRS-pain activity‡ | 2.8 (1.9 to 3.7) | 2.4 (1.5 to 3.3) | 0.4 (−0.8 to 1.5) |
| Lysholm§ | 89 (85 to 94) | 88 (84 to 93) | −1.0 (−6.2 to 4.1) |
| WOMET¶ | 72 (64 to 80) | 76 (68 to 84) | −3.8 (−13.8 to 6.2) |
| Tegner** | 5.4 (4.7 to 6.1) | 5.0 (4.4 to 5.7) | 0.3 (−0.6 to 1.3) |
| Satisfaction with knee function†† | 72 (64 to 80) | 70 (62 to 78) | 1.5 (−9.3 to 12.3) |
Data are presented as adjusted mean estimate with 95% CI in brackets.
*Adjusted for surgeon.
†The Knee Osteoarthritis Outcome Score ranges from 0 to 100, with higher scores indicating less pain and knee symptoms, less problems with ADL and sport and a better QoL.
‡The NRS for pain ranges from 0 to 10, with higher scores indicating more pain.
§The Lysholm score ranges from 0 to 100, with higher scores indicating less knee symptoms and higher levels of functioning.
¶The WOMET normalised score ranges from 0 to 100, with higher scores indicating a higher health-related quality of life.
**The Tegner scores ranges from 0 to 10, with higher scores indicating a higher activity level.
††Satisfaction with knee function is measured using a visual analogue scale ranging from 0 to 100, with higher scores indicating a higher patients’ satisfaction with their knee function.
ADL, activities of daily living; NRS, Numeric Rating Scale; QoL, quality of life; WOMET, Western Ontario Meniscal Evaluation Tool.
Serious adverse events
| Arthroscopic partial meniscectomy | Physical therapy | |
| Arthroscopic intervention for meniscal tear in contralateral knee | 1 | 1 |
| Rupture of ACL with ACL reconstruction | 0 | 1 |
| Arthroscopic intervention for failure of meniscal repair | 1 | 0 |
| Non-knee related surgery or hospital admission | 4* | 2† |
*1 surgery for carpal tunnel syndrome, 1 laparoscopy for abdominal cyst, 1 neurosurgery for brain tumour, 1 surgery for obstructive sleep apnoea syndrome
†1 surgery at the otorhinolaryngology department, 1 allergic reaction after intravenous contrast for contrast MRI for a femoral lesion
ACL, anterior cruciate ligament.