Literature DB >> 356754

Double blind trial in the treatment of herpes simplex and herpes zoster with adenine arabinoside and idoxuridine.

A Theodoridis, C Sivenas, A Vagena, J Capetanakis.   

Abstract

In a double blind trial adenine arabinoside (Vidarabine) and Idoxuridine (IDU) were tested in herpes simplex and herpes zoster infections. Adenine arabinoside covered 19 patients with HSV and 6 with HZ while IDU 19 with HSV and 6 with HZ. From the statistical analysis it was found that Vidarabine acts shorter than IDU in HSV P less than 0.01, while in HZ no significant difference P less than 0.5 was found, possibly due to the small number of patients tested.

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Year:  1978        PMID: 356754     DOI: 10.1007/bf00455387

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN: 0340-3696            Impact factor:   3.017


  4 in total

1.  Susceptibility of herpesviruses to three nucleoside analogues and their combinations and enhancement of the antiviral effect of acid pH.

Authors:  M Fiala; A W Chow; K Miyasaki; L B Guze
Journal:  J Infect Dis       Date:  1974-01       Impact factor: 5.226

2.  Treatment of zoster with idoxuridine in dimethyl sulphoxide. Results of two double-blind controlled trials.

Authors:  B E Juel-Jensen; F O MacCallum; A M Mackenzie; M C Pike
Journal:  Br Med J       Date:  1970-12-26

3.  Herpes simplex virus skin infection in man treated with idoxuridine in dimethyl sulphoxide. Results of double-blind controlled trial.

Authors:  F O MacCallum; B E Juel-Jensen
Journal:  Br Med J       Date:  1966-10-01

4.  Adenine arabinoside in idoxuridine unresponsive and intolerant herpetic keratitis.

Authors:  R A Hyndiuk; D S Hull; R O Schultz; G N Chin
Journal:  Am J Ophthalmol       Date:  1975-04       Impact factor: 5.258

  4 in total

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