Literature DB >> 35674845

Therapeutic effect of some natural active compounds for breast cancer.

Faik Gökalp1.   

Abstract

The extracts obtained from plants have been used in the treatment of many diseases since the earliest times. Today, it is of great importance to investigate the effects of the active molecules in these plant extracts at the molecular level together with the analysis. The effect of certain active compounds found in some plants, widely used as medicinal plants, on breast cancer has been investigated using docking. As a result of the docking scores obtained, it can be understood that the active molecules used in this study can be quite effective in controlling breast cancer. Promyelocytic leukemia is an important checkpoint from the literature for breast cancer and the docking energy values of Thymoquinone, Piperine and Carvacrol, as the active molecules in the control of this pathway. This study is very important when evaluated in terms of directing experimental studies by determining the most suitable active substances by comparing the activities of molecules in a short time.
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Breast cancer; Carvacrol; Docking; Piperine; Thymol; Thymoquinone

Year:  2022        PMID: 35674845     DOI: 10.1007/s12032-022-01704-0

Source DB:  PubMed          Journal:  Med Oncol        ISSN: 1357-0560            Impact factor:   3.064


  1 in total

Review 1.  Comparisons of calorie restriction and structured exercise on reductions in visceral and abdominal subcutaneous adipose tissue: a systematic review.

Authors:  Takashi Abe; Jun Seob Song; Zachary W Bell; Vickie Wong; Robert W Spitz; Yujiro Yamada; Jeremy P Loenneke
Journal:  Eur J Clin Nutr       Date:  2021-05-26       Impact factor: 4.016

  1 in total

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