Literature DB >> 3567461

Increase in acetylcholine concentrations in the brain of 'old' rats following treatment with pyrithioxin (Encephabol).

K J Martin, S Vyas.   

Abstract

Treatment of old rats, for two to three weeks, with pyrithioxin led to an increase in the levels of endogenous acetylcholine (ACh) in the cortex and the striatum but not in the hippocampus. Pretreatment of old rats with pyrithioxin also increased the resting release and the K+ stimulated release of radioactive ACh from brain slices in vitro.

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Year:  1987        PMID: 3567461      PMCID: PMC1917181          DOI: 10.1111/j.1476-5381.1987.tb11206.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  19 in total

1.  Regional mapping of neostriatal neurotransmitter systems as a function of aging.

Authors:  R Strong; T Samorajski; Z Gottesfeld
Journal:  J Neurochem       Date:  1982-09       Impact factor: 5.372

2.  Effect of dopamine agonists and neuroleptic agents on striatal acetylcholine transmission in the rat: evidence against dopamine receptor multiplicity.

Authors:  B Scatton
Journal:  J Pharmacol Exp Ther       Date:  1982-01       Impact factor: 4.030

Review 3.  On the mechanism of action of Encephabol.

Authors:  K J Martin
Journal:  J Int Med Res       Date:  1983       Impact factor: 1.671

Review 4.  Alzheimer's disease: a disorder of cortical cholinergic innervation.

Authors:  J T Coyle; D L Price; M R DeLong
Journal:  Science       Date:  1983-03-11       Impact factor: 47.728

Review 5.  Problems in the organization and control of acetylcholine synthesis in brain neurons.

Authors:  S Tucek
Journal:  Prog Biophys Mol Biol       Date:  1984       Impact factor: 3.667

6.  Modulation by GABA of cholinergic transmission in the striatum.

Authors:  B Scatton; G Bartholini
Journal:  Brain Res       Date:  1980-02-03       Impact factor: 3.252

Review 7.  The pharmacology of memory: a neurobiological perspective.

Authors:  L R Squire; H P Davis
Journal:  Annu Rev Pharmacol Toxicol       Date:  1981       Impact factor: 13.820

8.  Application to mammalian tissues of the chemiluminescent method for detecting acetylcholine.

Authors:  M Israël; B Lesbats
Journal:  J Neurochem       Date:  1982-07       Impact factor: 5.372

Review 9.  The cholinergic hypothesis of geriatric memory dysfunction.

Authors:  R T Bartus; R L Dean; B Beer; A S Lippa
Journal:  Science       Date:  1982-07-30       Impact factor: 47.728

10.  Choline and acetylcholine metabolism in rat neostriatal slices.

Authors:  M H Weiler; I J Bak; D J Jenden
Journal:  J Neurochem       Date:  1983-08       Impact factor: 5.372

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  1 in total

Review 1.  Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs.

Authors:  Matěj Malík; Pavel Tlustoš
Journal:  Nutrients       Date:  2022-08-17       Impact factor: 6.706

  1 in total

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