Literature DB >> 35673511

Anti-diabetic potential of Urtica Dioica: current knowledge and future direction.

Anita Chehri1,2, Reza Yarani3, Zahra Yousefi4, Tannaz Novin Bahador5, Seyed Kazem Shakouri5, Alireza Ostadrahimi6, Majid Mobasseri7, Flemming Pociot3,8, Mostafa Araj-Khodaei2,9.   

Abstract

Aim: This review summarizes studies on the anti-diabetic effect of Urtica Dioica (UD) in Type-2-diabetes. Materials and methods: We studied worldwide traditional medicines, old texts, and published literature for anti-diabetic effect of UD. Electronic databases comprising PubMed, Web of Science, Science Direct, Scopus and Google Scholar were searched to collect articles published between 1990 and 2021 years.
Results: Our literature investigation suggests UD as a glucose lowering, blood lipid regulating, anti-inflammatory and anti-oxidation plant. Conclusions: UD's anti-diabetic properties make it potential traditional therapeutics for lowering the clinical manifestations of T2DM through affecting hyperglycemia and therefore suggest it as a proper medication with no or limited side effects. © Springer Nature Switzerland AG 2021.

Entities:  

Keywords:  Diabetes mellitus; Insulin; Traditional medicine; Urtica dioica

Year:  2022        PMID： 35673511      PMCID： PMC9167344          DOI： 10.1007/s40200-021-00942-9

Source DB:  PubMed          Journal:  J Diabetes Metab Disord        ISSN： 2251-6581


  48 in total

1.  Protective role of Urtica dioica L. (Urticaceae) extract on hepatocytes morphometric changes in STZ diabetic Wistar rats.

Authors:  Mohammad Jafar Golalipour; Soraya Ghafari; Mohammad Afshar
Journal:  Turk J Gastroenterol       Date:  2010-09       Impact factor: 1.852

2.  Inhibition of alpha-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs.

Authors:  Seçil Onal; Suna Timur; Burcu Okutucu; Figen Zihnioğlu
Journal:  Prep Biochem Biotechnol       Date:  2005       Impact factor: 2.162

3.  Positive relationship between plasma leptin level and hypertension.

Authors:  Anoop Shankar; Jie Xiao
Journal:  Hypertension       Date:  2010-08-16       Impact factor: 10.190

Review 4.  Global aetiology and epidemiology of type 2 diabetes mellitus and its complications.

Authors:  Yan Zheng; Sylvia H Ley; Frank B Hu
Journal:  Nat Rev Endocrinol       Date:  2017-12-08       Impact factor: 43.330

5.  The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats.

Authors:  M K Türkdoğan; H Ozbek; Z Yener; I Tuncer; I Uygan; E Ceylan
Journal:  Phytother Res       Date:  2003-09       Impact factor: 5.878

6.  Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor.

Authors:  R M Palmer; A G Ferrige; S Moncada
Journal:  Nature       Date:  1987 Jun 11-17       Impact factor: 49.962

7.  Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats.

Authors:  Bijan Farzami; D Ahmadvand; S Vardasbi; F J Majin; Sh Khaghani
Journal:  J Ethnopharmacol       Date:  2003-11       Impact factor: 4.360

8.  Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice.

Authors:  Soo-Mi Jeong; Min-Jung Kang; Ha-Neul Choi; Ji-Hye Kim; Jung-In Kim
Journal:  Nutr Res Pract       Date:  2012-06-30       Impact factor: 1.926

9.  Effects of Urtica dioica on hepatic ischemia-reperfusion injury in rats.

Authors:  Hayati Kandis; Sami Karapolat; Umran Yildirim; Ayhan Saritas; Suat Gezer; Ramazan Memisogullari
Journal:  Clinics (Sao Paulo)       Date:  2010       Impact factor: 2.365

10.  Silymarin, Olibanum, and Nettle, A Mixed Herbal Formulation in the Treatment of Type II Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial.

Authors:  Nahid Khalili; Reza Fereydoonzadeh; Reza Mohtashami; Saeed Mehrzadi; Mojtaba Heydari; Hasan Fallah Huseini
Journal:  J Evid Based Complementary Altern Med       Date:  2017-03-21
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  1 in total

1.  Ethnopharmacological Effects of Urtica dioica, Matricaria chamomilla, and Murraya koenigii on Rotenone-Exposed D. melanogaster: An Attenuation of Cellular, Biochemical, and Organismal Markers.

Authors:  Shabnam Shabir; Sumaira Yousuf; Sandeep Kumar Singh; Emanuel Vamanu; Mahendra P Singh
Journal:  Antioxidants (Basel)       Date:  2022-08-21
  1 in total

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