| Literature DB >> 35673457 |
Mandana Hasanzad1,2, Negar Sarhangi2, Anoosh Naghavi3, Ehsan Ghavimehr1, Fatemeh Khatami4, Sima Ehsani Chimeh5, Bagher Larijani6, Hamid Reza Aghaei Meybodi2.
Abstract
Genomic medicine has created a great deal of hope since the completion of the Human Genome Project (HGP). Genomic medicine promises disease prevention and early diagnosis in the context of precision medicine. Precision medicine as a scientific discipline has introduced as an evolution in medicine. The rapid growth of high-development technologies permits the assessment of biological systems. Study of the integrated profiles of omics, such as genome, transcriptome, proteome and other omics information lead to significant advances in personalized and precision medicine. In the context of precision medicine, pharmacogenomics can play an important role in order to discriminate responders and non-responders to medications and avoiding toxicity and achieving the optimum dose. So precision medicine in accordance with genomic medicine will transform medicine from conventional evidence-based medicine in the diagnosis and treatment towards precision based-medicine. In this review, we have summarized the related issues for genomic medicine and precision medicine. © Springer Nature Switzerland AG 2021.Entities:
Keywords: GWAS; Genomic medicine; Omics; Pharmacogenomics; Precision medicine
Year: 2021 PMID: 35673457 PMCID: PMC9167337 DOI: 10.1007/s40200-021-00880-6
Source DB: PubMed Journal: J Diabetes Metab Disord ISSN: 2251-6581