Literature DB >> 35669295

Revisiting the Obesity Paradox in Health Care Expenditures Among Adults With Diabetes.

Virender Kumar1, William Encinosa2,3.   

Abstract

Recent studies of diabetes suggest an obesity paradox: mortality risk increases with weight in people without diabetes but decreases with weight in people with diabetes. A recent study also reports the paradox more generally with health care utilization. Whether this paradox in health care utilization and spending is causal or instead the result of empirical biases and confounding factors has yet to be examined in detail. This study set out to examine changes in the relationship between BMI and health care expenditures in populations with versus without diabetes, controlling for confounding risk factors. It found that the obesity paradox does not exist and is the result of statistical biases such as confounding and reverse causation. Obesity is not cost-saving for people with diabetes. Thus, insurers and physicians should renew efforts to prevent obesity in people with diabetes.
© 2022 by the American Diabetes Association.

Entities:  

Year:  2022        PMID: 35669295      PMCID: PMC9160553          DOI: 10.2337/cd20-0122

Source DB:  PubMed          Journal:  Clin Diabetes        ISSN: 0891-8929


  27 in total

Review 1.  Physical inactivity, excess adiposity and premature mortality.

Authors:  P T Katzmarzyk; I Janssen; C I Ardern
Journal:  Obes Rev       Date:  2003-11       Impact factor: 9.213

2.  The obesity paradox in type 2 diabetes mellitus: relationship of body mass index to prognosis: a cohort study.

Authors:  Pierluigi Costanzo; John G F Cleland; Pierpaolo Pellicori; Andrew L Clark; David Hepburn; Eric S Kilpatrick; Pasquale Perrone-Filardi; Jufen Zhang; Stephen L Atkin
Journal:  Ann Intern Med       Date:  2015-05-05       Impact factor: 25.391

3.  Mortality in people with type 2 diabetes in the UK.

Authors:  H E Mulnier; H E Seaman; V S Raleigh; S S Soedamah-Muthu; H M Colhoun; R A Lawrenson
Journal:  Diabet Med       Date:  2006-05       Impact factor: 4.359

4.  Obesity paradox in people newly diagnosed with type 2 diabetes with and without prior cardiovascular disease.

Authors:  G Thomas; K Khunti; V Curcin; M Molokhia; C Millett; A Majeed; S Paul
Journal:  Diabetes Obes Metab       Date:  2013-10-29       Impact factor: 6.577

5.  Association between body-mass index and risk of death in more than 1 million Asians.

Authors:  Wei Zheng; Dale F McLerran; Betsy Rolland; Xianglan Zhang; Manami Inoue; Keitaro Matsuo; Jiang He; Prakash Chandra Gupta; Kunnambath Ramadas; Shoichiro Tsugane; Fujiko Irie; Akiko Tamakoshi; Yu-Tang Gao; Renwei Wang; Xiao-Ou Shu; Ichiro Tsuji; Shinichi Kuriyama; Hideo Tanaka; Hiroshi Satoh; Chien-Jen Chen; Jian-Min Yuan; Keun-Young Yoo; Habibul Ahsan; Wen-Harn Pan; Dongfeng Gu; Mangesh Suryakant Pednekar; Catherine Sauvaget; Shizuka Sasazuki; Toshimi Sairenchi; Gong Yang; Yong-Bing Xiang; Masato Nagai; Takeshi Suzuki; Yoshikazu Nishino; San-Lin You; Woon-Puay Koh; Sue K Park; Yu Chen; Chen-Yang Shen; Mark Thornquist; Ziding Feng; Daehee Kang; Paolo Boffetta; John D Potter
Journal:  N Engl J Med       Date:  2011-02-24       Impact factor: 91.245

6.  Body mass index and the risk of all-cause mortality among patients with type 2 diabetes mellitus.

Authors:  Wenhui Zhao; Peter T Katzmarzyk; Ronald Horswell; Yujie Wang; Weiqin Li; Jolene Johnson; Steven B Heymsfield; William T Cefalu; Donna H Ryan; Gang Hu
Journal:  Circulation       Date:  2014-11-05       Impact factor: 29.690

7.  Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old.

Authors:  Kenneth F Adams; Arthur Schatzkin; Tamara B Harris; Victor Kipnis; Traci Mouw; Rachel Ballard-Barbash; Albert Hollenbeck; Michael F Leitzmann
Journal:  N Engl J Med       Date:  2006-08-22       Impact factor: 91.245

8.  Body-mass index and mortality in a prospective cohort of U.S. adults.

Authors:  E E Calle; M J Thun; J M Petrelli; C Rodriguez; C W Heath
Journal:  N Engl J Med       Date:  1999-10-07       Impact factor: 91.245

9.  Predictors of mortality over 8 years in type 2 diabetic patients: Translating Research Into Action for Diabetes (TRIAD).

Authors:  Laura N McEwen; Andrew J Karter; Beth E Waitzfelder; Jesse C Crosson; David G Marrero; Carol M Mangione; William H Herman
Journal:  Diabetes Care       Date:  2012-03-19       Impact factor: 19.112

10.  Obesity paradox: conditioning on disease enhances biases in estimating the mortality risks of obesity.

Authors:  Samuel H Preston; Andrew Stokes
Journal:  Epidemiology       Date:  2014-05       Impact factor: 4.822

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