Literature DB >> 3566753

Effects of myosin light-chain kinase inhibitor on catecholamine secretion from rat pheochromocytoma PC12h cells.

T Nagatsu, H Suzuki, K Kiuchi, M Saitoh, H Hidaka.   

Abstract

Release of dopamine from rat pheochromocytoma PC12h cells by high K+ (50 mM) was inhibited by a specific inhibitor of myosin light-chain kinase (ML-9) dose-dependently. The myosin light-chain kinase inhibitor also specifically inhibited the phosphorylation of a 20 KDa protein by myosin light-chain kinase. Myosin light chain kinase may play a stimulatory role in the release reaction of catecholamines from the rat pheochromocytoma cells.

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Year:  1987        PMID： 3566753     DOI： 10.1016/0006-291x(87)90357-3

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  7 in total

1.  Phosphorylation and subcellular translocation of endothelial nitric oxide synthase.

Authors:  T Michel; G K Li; L Busconi
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

2.  An Assessment of the Permeation Enhancer, 1-phenyl-piperazine (PPZ), on Paracellular Flux Across Rat Intestinal Mucosae in Ussing Chambers.

Authors:  V A Bzik; D J Brayden
Journal:  Pharm Res       Date:  2016-07-07       Impact factor: 4.200

3.  Functional reconstitution in Escherichia coli of the yeast mitochondrial matrix peptidase from its two inactive subunits.

Authors:  V Géli
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

4.  Naphthalenesulfonamide derivatives ML9 and W7 inhibit catecholamine secretion in intact and permeabilized chromaffin cells.

Authors:  J A Reig; S Viniegra; J J Ballesta; M Palmero; L M Guitierrez
Journal:  Neurochem Res       Date:  1993-03       Impact factor: 3.996

5.  Myosin light chain kinase inhibitors induce retraction of mature oligodendrocyte processes.

Authors:  María G Thomas; Tomás A Santa Coloma; Jorge Correale; Graciela L Boccacci
Journal:  Neurochem Res       Date:  2002-11       Impact factor: 3.996

6.  Phosphorylation of myosin light chain from adrenomedullary chromaffin cells in culture.

Authors:  L M Gutierrez; M J Hidalgo; M Palmero; J J Ballesta; J A Reig; A G Garcia; S Viniegra
Journal:  Biochem J       Date:  1989-12-01       Impact factor: 3.857

7.  Calcium/calmodulin transduces thrombin-stimulated secretion: studies in intact and minimally permeabilized human umbilical vein endothelial cells.

Authors:  K A Birch; J S Pober; G B Zavoico; A R Means; B M Ewenstein
Journal:  J Cell Biol       Date:  1992-09       Impact factor: 10.539
  7 in total

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