Literature DB >> 35667407

Rate of Autoactivation Determines Pancreatitis Phenotype in Trypsinogen Mutant Mice.

Alexandra Demcsák1, Miklós Sahin-Tóth2.   

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Year:  2022        PMID： 35667407      PMCID： PMC9398983          DOI： 10.1053/j.gastro.2022.06.001

Source DB:  PubMed          Journal:  Gastroenterology        ISSN： 0016-5085            Impact factor:   33.883


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  9 in total

1.  Trypsin activity governs increased susceptibility to pancreatitis in mice expressing human PRSS1R122H.

Authors:  Fu Gui; Yuebo Zhang; Jianhua Wan; Xianbao Zhan; Yao Yao; Yinghua Li; Ashley N Haddock; Ji Shi; Jia Guo; Jiaxiang Chen; Xiaohui Zhu; Brandy H Edenfield; Lu Zhuang; Cheng Hu; Ying Wang; Debabrata Mukhopadhyay; Evette S Radisky; Lizhi Zhang; Aurelia Lugea; Stephen J Pandol; Yan Bi; Baoan Ji
Journal:  J Clin Invest       Date:  2020-01-02       Impact factor: 14.808

2.  Wild-Type Human PRSS2 and PRSS1R122H Cooperatively Initiate Spontaneous Hereditary Pancreatitis in Transgenic Mice.

Authors:  Jiale Wang; Jianhua Wan; Lingxiang Wang; Stephen J Pandol; Yan Bi; Baoan Ji
Journal:  Gastroenterology       Date:  2022-03-11       Impact factor: 33.883

3.  Mutation That Promotes Activation of Trypsinogen Increases Severity of Secretagogue-Induced Pancreatitis in Mice.

Authors:  Zsanett Jancsó; Miklós Sahin-Tóth
Journal:  Gastroenterology       Date:  2019-11-18       Impact factor: 22.682

Review 4.  Genetics, Cell Biology, and Pathophysiology of Pancreatitis.

Authors:  Julia Mayerle; Matthias Sendler; Eszter Hegyi; Georg Beyer; Markus M Lerch; Miklós Sahin-Tóth
Journal:  Gastroenterology       Date:  2019-01-18       Impact factor: 22.682

5.  Transgenic expression of human PRSS2 exacerbates pancreatitis in mice.

Authors:  Jianhua Wan; Ashley Haddock; Brandy Edenfield; Baoan Ji; Yan Bi
Journal:  Gut       Date:  2020-01-23       Impact factor: 23.059

6.  Chronic progression of cerulein-induced acute pancreatitis in trypsinogen mutant mice.

Authors:  Zsanett Jancsó; Miklós Sahin-Tóth
Journal:  Pancreatology       Date:  2022-01-14       Impact factor: 3.996

Review 7.  Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway.

Authors:  Eszter Hegyi; Miklós Sahin-Tóth
Journal:  Dig Dis Sci       Date:  2017-05-23       Impact factor: 3.199

8.  Engineering mouse cationic trypsinogen for rapid and selective activation by cathepsin B.

Authors:  Alexandra Demcsák; Andrea Geisz; Miklós Sahin-Tóth
Journal:  Sci Rep       Date:  2019-06-24       Impact factor: 4.379

9.  A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation.

Authors:  Andrea Geisz; Miklós Sahin-Tóth
Journal:  Nat Commun       Date:  2018-11-28       Impact factor: 14.919
  9 in total

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