Anh D Bui1,2, Anna L Diep2, Qiyin Lin3, Donald S Minckler4, Andrew W Browne4,5,6, Angeline L Wang4,7. 1. Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA. 2. School of Medicine, University of California, Irvine, Irvine, CA, USA. 3. Irvine Materials Research Institute, University of California, Irvine, Irvine, CA, USA. 4. Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, USA. 5. Department of Biomedical Engineering, University of California, Irvine, Irvine, CA, USA. 6. Institute for Clinical and Translational Science, University of California, Irvine, Irvine, CA, USA. 7. Department of Ophthalmology, UT Southwestern Medical Center, Dallas, TX, USA.
Abstract
Purpose: This report aims to characterize ocular changes in a case of ocular siderosis with iron toxicity using multimodal imaging and electroretinography. Methods: A 34-year-old woman presented with ocular siderosis of the left eye following penetrating injury with an iron-containing foreign body. The patient's uncorrected visual acuities were 20/60 and 20/150 in the right and left eye, respectively, with abnormal pupillary function and presence of a cataract in the left eye. She underwent successful intraocular foreign body removal and cataract surgery with no postoperative complications. Cone contrast threshold (CCT), full-field electroretinogram, spectral-domain optical coherence tomography (OCT), and OCT angiography (OCTA) were used to characterize ocular alterations preoperatively and postoperatively. Results: CCT color vision testing showed abnormal color vision, and OCTA revealed increased vascular flow density associated with the foreign body. Conclusions: CCT color vision testing, OCTA, OCT, and full-field electroretinogram can characterize retinal changes in cases of ocular siderosis.
Purpose: This report aims to characterize ocular changes in a case of ocular siderosis with iron toxicity using multimodal imaging and electroretinography. Methods: A 34-year-old woman presented with ocular siderosis of the left eye following penetrating injury with an iron-containing foreign body. The patient's uncorrected visual acuities were 20/60 and 20/150 in the right and left eye, respectively, with abnormal pupillary function and presence of a cataract in the left eye. She underwent successful intraocular foreign body removal and cataract surgery with no postoperative complications. Cone contrast threshold (CCT), full-field electroretinogram, spectral-domain optical coherence tomography (OCT), and OCT angiography (OCTA) were used to characterize ocular alterations preoperatively and postoperatively. Results: CCT color vision testing showed abnormal color vision, and OCTA revealed increased vascular flow density associated with the foreign body. Conclusions: CCT color vision testing, OCTA, OCT, and full-field electroretinogram can characterize retinal changes in cases of ocular siderosis.
Entities:
Keywords:
OCT angiography; cular siderosis; full-field electroretinogram; intraocular foreign body; iron toxicity; optical coherence tomography
Authors: Thomas S Hwang; Simon S Gao; Liang Liu; Andreas K Lauer; Steven T Bailey; Christina J Flaxel; David J Wilson; David Huang; Yali Jia Journal: JAMA Ophthalmol Date: 2016-04 Impact factor: 7.389
Authors: Urmi Mehta; Anna Diep; Kevin Nguyen; Bryan Le; Clara Yuh; Caroline Frambach; John Doan; Ang Wei; Anton M Palma; Marjan Farid; Sumit Garg; Sanjay Kedhar; Matthew Wade; Kailey A Marshall; Kimberly A Jameson; M Cristina Kenney; Andrew W Browne Journal: Transl Vis Sci Technol Date: 2020-11-03 Impact factor: 3.283