Literature DB >> 3566336

Comparisons of in vivo and in vitro photosensitivities and DNA repair in fibroblast and keratinocyte cells.

H Machino, S Shiraishi, Y Miki.   

Abstract

Minimal erythema dose of ultraviolet light correlated significantly with the UV-sensitivity of fibroblast cells from 5 patients with xeroderma pigmentosum, 13 patients with keratinocytic neoplasms of the skin, and 21 control subjects, but not with that of cells from 6 patients with photosensitive dermatitis. In unscheduled DNA synthesis after UV irradiation, the number of grains per nucleus was much less in keratinocytes than in fibroblasts, but the relative dose-response relationship was similar. This indicates that keratinocytes can also be used in vitro UV-sensitivity studies.

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Year:  1986        PMID： 3566336     DOI： 10.1007/bf00417533

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  16 in total

Review 1.  Repair deficient human disorders and cancer.

Authors:  R B Setlow
Journal:  Nature       Date:  1978-02-23       Impact factor: 49.962

2.  Xeroderma pigmentosum epidermal cells with normal UV-induced thymidine incorporation.

Authors:  J H Robbins; W R Levis; A E Miller
Journal:  J Invest Dermatol       Date:  1972-11       Impact factor: 8.551

3.  Defective repair replication of DNA in xeroderma pigmentosum.

Authors:  J E Cleaver
Journal:  Nature       Date:  1968-05-18       Impact factor: 49.962

4.  Excision repair of mouse and human fibroblast cells, and a factor affecting the amount of UV-induced unscheduled DNA synthesis.

Authors:  T Yagi; O Nikaido; H Takebe
Journal:  Mutat Res       Date:  1984 Sep-Oct       Impact factor: 2.433

5.  Ultraviolet-induced dna repair synthesis in lymphocytes from patients with actinic keratosis.

Authors:  B Lambert; U Ringborg; G Swanbeck
Journal:  J Invest Dermatol       Date:  1976-11       Impact factor: 8.551

6.  DNA repair following ultraviolet and N-ethyl-N-nitrosourea treatment of cells cultured from human fetal brain, intestine, kidney, liver, and skin.

Authors:  R E Gibson-D'Ambrosio; Y Leong; S M D'Ambrosio
Journal:  Cancer Res       Date:  1983-12       Impact factor: 12.701

7.  Comparative studies of host-cell reactivation, colony forming ability and excision repair after UV irradiation of xeroderma pigmentosum, normal human and some other mammalian cells.

Authors:  H Takebe; S Nii; M I Ishii; H Utsumi
Journal:  Mutat Res       Date:  1974-12       Impact factor: 2.433

8.  Xeroderma pigmentosum neurological abnormalities correlate with colony-forming ability after ultraviolet radiation.

Authors:  A D Andrews; S F Barrett; J H Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  1978-04       Impact factor: 11.205

9.  DNA-repair after UV-irradiation in skin fibroblasts from patients with actinic keratosis.

Authors:  E Sbano; L Andreassi; M Fimiani; A Valentino; R Baiocchi
Journal:  Arch Dermatol Res       Date:  1978-06-29       Impact factor: 3.017

10.  Cytogenetic studies in a patient with porokeratosis of Mibelli, multiple cancers and a forme fruste of Werner's syndrome.

Authors:  H Machino; Y Miki; T Teramoto; S Shiraishi; M S Sasaki
Journal:  Br J Dermatol       Date:  1984-11       Impact factor: 9.302
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