Literature DB >> 35662655

Insights into the biology of IL-9 in asthma.

Taylor A Doherty1, David H Broide2.   

Abstract

Entities:  

Keywords:  IL-9; arginase-1; asthma; macrophages

Mesh：

Substances：

Year:  2022        PMID： 35662655      PMCID： PMC9463120          DOI： 10.1016/j.jaci.2022.05.015

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN： 0091-6749            Impact factor:   14.290


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  10 in total

1.  IL-9 and its receptor in allergic and nonallergic lung disease: increased expression in asthma.

Authors:  A Shimbara; P Christodoulopoulos; A Soussi-Gounni; R Olivenstein; Y Nakamura; R C Levitt; N C Nicolaides; K J Holroyd; A Tsicopoulos; J J Lafitte; B Wallaert; Q A Hamid
Journal:  J Allergy Clin Immunol       Date:  2000-01       Impact factor: 10.793

2.  An IL-9-pulmonary macrophage axis defines the allergic lung inflammatory environment.

Authors:  Yongyao Fu; Jocelyn Wang; Baohua Zhou; Abigail Pajulas; Hongyu Gao; Baskar Ramdas; Byunghee Koh; Benjamin J Ulrich; Shuangshuang Yang; Reuben Kapur; Jean-Christophe Renauld; Sophie Paczesny; Yunlong Liu; Robert M Tighe; Paula Licona-Limón; Richard A Flavell; Shogo Takatsuka; Daisuke Kitamura; Robert S Tepper; Jie Sun; Mark H Kaplan
Journal:  Sci Immunol       Date:  2022-02-18

3.  Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes.

Authors:  Veit J Erpenbeck; Jens M Hohlfeld; Brunhild Volkmann; Andreas Hagenberg; Henning Geldmacher; Armin Braun; Norbert Krug
Journal:  J Allergy Clin Immunol       Date:  2003-06       Impact factor: 10.793

4.  Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma.

Authors:  Grégory Seumois; Ciro Ramírez-Suástegui; Benjamin J Schmiedel; Shu Liang; Bjoern Peters; Alessandro Sette; Pandurangan Vijayanand
Journal:  Sci Immunol       Date:  2020-06-12

5.  Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance.

Authors:  Pejman Soroosh; Taylor A Doherty; Wei Duan; Amit Kumar Mehta; Heonsik Choi; Yan Fei Adams; Zbigniew Mikulski; Naseem Khorram; Peter Rosenthal; David H Broide; Michael Croft
Journal:  J Exp Med       Date:  2013-04-01       Impact factor: 14.307

6.  Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma.

Authors:  Joseph M Parker; Chad K Oh; Craig LaForce; S David Miller; David S Pearlman; Chenxiong Le; Gabriel J Robbie; Wendy I White; Barbara White; Nestor A Molfino
Journal:  BMC Pulm Med       Date:  2011-02-28       Impact factor: 3.317

7.  A randomized, controlled trial to evaluate the effect of an anti-interleukin-9 monoclonal antibody in adults with uncontrolled asthma.

Authors:  Chad K Oh; Richard Leigh; Kimmie K McLaurin; Keunpyo Kim; Micki Hultquist; Nestor A Molfino
Journal:  Respir Res       Date:  2013-09-19

Review 8.  An Update on Interleukin-9: From Its Cellular Source and Signal Transduction to Its Role in Immunopathogenesis.

Authors:  Sushmita Chakraborty; Katharina F Kubatzky; Dipendra Kumar Mitra
Journal:  Int J Mol Sci       Date:  2019-04-29       Impact factor: 5.923

9.  Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness.

Authors:  U A Temann; G P Geba; J A Rankin; R A Flavell
Journal:  J Exp Med       Date:  1998-10-05       Impact factor: 14.307
  10 in total
  1 in total

Review 1.  Current Understanding of Asthma Pathogenesis and Biomarkers.

Authors:  Nazia Habib; Muhammad Asghar Pasha; Dale D Tang
Journal:  Cells       Date:  2022-09-05       Impact factor: 7.666
  1 in total

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