Literature DB >> 3566252

Pharmacokinetics of cefoperazone and tobramycin alone and in combination.

B J Guglielmo, J F Flaherty, T M Woods, G LaFollette, J G Gambertoglio.   

Abstract

Certain beta-lactams have been shown to increase the clearance of tobramycin. We evaluated the pharmacokinetics of cefoperazone and tobramycin, alone and in combination, in healthy volunteers. No significant alteration in pharmacokinetic behavior was noted for cefoperazone or tobramycin alone or in combination.

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Year:  1987        PMID： 3566252      PMCID： PMC174703          DOI： 10.1128/AAC.31.2.264

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  Inactivation of gentamicin by penicillins in patients with renal failure.

Authors:  F R Ervin; W E Bullock; C E Nuttall
Journal:  Antimicrob Agents Chemother       Date:  1976-06       Impact factor: 5.191

Review 2.  Antibiotic synergism and antimicrobial combinations in clinical infections.

Authors:  G M Eliopoulos; R C Moellering
Journal:  Rev Infect Dis       Date:  1982 Mar-Apr

3.  Significance of antimicrobial synergism for the outcome of gram negative sepsis.

Authors:  J Klastersky; F Meunier-Carpentier; J M Prevost
Journal:  Am J Med Sci       Date:  1977 Mar-Apr       Impact factor: 2.378

4.  Interactions of moxalactam and tobramycin in normal volunteers and in patients with impaired renal function.

Authors:  G R Aronoff; M E Brier; D M Nierste; R S Sloan
Journal:  J Infect Dis       Date:  1984-01       Impact factor: 5.226

5.  Synergism at clinically attainable concentrations of aminoglycoside and beta-lactam antibiotics.

Authors:  T M Hooton; A D Blair; M Turck; G W Counts
Journal:  Antimicrob Agents Chemother       Date:  1984-10       Impact factor: 5.191

6.  Effect of time and concentration upon interaction between gentamicin, tobramycin, Netilmicin, or amikacin and carbenicillin or ticarcillin.

Authors:  L K Pickering; P Gearhart
Journal:  Antimicrob Agents Chemother       Date:  1979-04       Impact factor: 5.191
  6 in total
  1 in total

1.  Antimicrobial breakpoints for gram-negative aerobic bacteria based on pharmacokinetic-pharmacodynamic models with Monte Carlo simulation.

Authors:  Christopher R Frei; Nathan P Wiederhold; David S Burgess
Journal:  J Antimicrob Chemother       Date:  2008-02-04       Impact factor: 5.790
  1 in total

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