Literature DB >> 35659101

Short Bowel Syndrome and Dysmotility.

Muralidhar H Premkumar1.   

Abstract

Due to recent advances, the mortality due to short bowel syndrome (SBS) has significantly decreased, but the morbidities are still high. Morbidities arising specifically due to dysmotility in SBS include feeding intolerance, prolonged dependence on parenteral nutrition, and associated complications such as intestinal failure associated liver disease, and bloodstream infections. The understanding of the pathogenesis of dysmotility in SBS has improved vastly. However, the tools to diagnose dysmotility in SBS in infants are restrictive, and the medical therapies to treat dysmotility are limited. Surgical techniques available for the treatment after failure of conservative management of dysmotility offer hope but carry their associated risks. The evidence to support either the medical therapies or the surgical techniques to treat dysmotility in SBS in children is scarce and weak. Development of newer therapies and efforts to build evidence to support currently available treatments in treating dysmotility in SBS is needed.
Copyright © 2022 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Antidiarrheal agents; Hypermotility; Hypomotility; Intestinal failure; Prokinetics; Promotility agents; SBS; Short gut

Mesh:

Year:  2022        PMID: 35659101     DOI: 10.1016/j.clp.2022.02.013

Source DB:  PubMed          Journal:  Clin Perinatol        ISSN: 0095-5108            Impact factor:   3.430


  1 in total

1.  Motility disorders in children with intestinal failure: a national tertiary referral center experience.

Authors:  Audelia Eshel Fuhrer; Stephanie Sukhotnik; Hadar Moran-Lev; Keren Kremer; Yoav Ben-Shahar; Igor Sukhotnik
Journal:  Pediatr Surg Int       Date:  2022-09-17       Impact factor: 2.003

  1 in total

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