Literature DB >> 35654967

Designer protein circuits enable safe cancer immunotherapy.

Mohamad Hamieh, Maria Themeli.   

Abstract

Entities:  

Keywords:  Medical research; Synthetic biology

Mesh：

Year:  2022        PMID： 35654967     DOI： 10.1038/d41586-022-01528-y

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  5 in total

1.  Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting.

Authors:  Shivani Srivastava; Alexander I Salter; Denny Liggitt; Sushma Yechan-Gunja; Megha Sarvothama; Kirsten Cooper; Kimberly S Smythe; Jarrod A Dudakov; Robert H Pierce; Christoph Rader; Stanley R Riddell
Journal:  Cancer Cell       Date:  2019-03-18       Impact factor: 31.743

2.  Modular design of synthetic receptors for programmed gene regulation in cell therapies.

Authors:  Iowis Zhu; Raymond Liu; Julie M Garcia; Axel Hyrenius-Wittsten; Dan I Piraner; Josef Alavi; Divya V Israni; Bin Liu; Ahmad S Khalil; Kole T Roybal
Journal:  Cell       Date:  2022-04-14       Impact factor: 66.850

3.  Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits.

Authors:  Kole T Roybal; Levi J Rupp; Leonardo Morsut; Whitney J Walker; Krista A McNally; Jason S Park; Wendell A Lim
Journal:  Cell       Date:  2016-01-28       Impact factor: 41.582

4.  Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors.

Authors:  Leonardo Morsut; Kole T Roybal; Xin Xiong; Russell M Gordley; Scott M Coyle; Matthew Thomson; Wendell A Lim
Journal:  Cell       Date:  2016-01-28       Impact factor: 41.582

5.  Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.

Authors:  Kole T Roybal; Jasper Z Williams; Leonardo Morsut; Levi J Rupp; Isabel Kolinko; Joseph H Choe; Whitney J Walker; Krista A McNally; Wendell A Lim
Journal:  Cell       Date:  2016-09-29       Impact factor: 41.582
  5 in total

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