Literature DB >> 35653329

Correction: Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma.

Erik Koehne, Nina Zander, Miriam Rodi, Jana Held, Wolfgang Hoffmann, Rella Zoleko-Manego, Michael Ramharter, Ghyslain Mombo-Ngoma, Peter G Kremsner, Andrea Kreidenweiss.   

Abstract

[This corrects the article DOI: 10.1371/journal.pntd.0009511.].

Entities:  

Year:  2022        PMID: 35653329      PMCID: PMC9162304          DOI: 10.1371/journal.pntd.0010512

Source DB:  PubMed          Journal:  PLoS Negl Trop Dis        ISSN: 1935-2727


There is an error in Table 2. The line shifted some data into the incorrect drug candidates. Please see the correct Table 2 here.
Table 2

Drug activity against ex vivo adult worms (step 2).

DrugConcentrationin µMNo. of worms tested% affected% dead
No drugNA1200
DMSO0.1%1000
Praziquantel1120100
Methylene blue5173559
10120100
30120100
30*60100
Pyronaridine515060
10114555
30120100
30*60100
Methylene blue, pyronaridine, and praziquantel (positive control) were exposed to the respective concentrations for 7 days (* for 24 h) followed by a 7 days drug wash-out in vitro culture.”No drug” and DMSO were the negative controls. Pooled data obtained from 3 experiments per drug are displayed.
  1 in total

1.  Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma.

Authors:  Erik Koehne; Nina Zander; Miriam Rodi; Jana Held; Wolfgang Hoffmann; Rella Zoleko-Manego; Michael Ramharter; Ghyslain Mombo-Ngoma; Peter G Kremsner; Andrea Kreidenweiss
Journal:  PLoS Negl Trop Dis       Date:  2021-06-24
  1 in total

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