Literature DB >> 356524

Multidisciplinary treatment for central nervous system tumours with nitrosourea compounds.

P Paoletti, G Robustelli della Cuna, R Knerich, M R Strada.   

Abstract

The authors report the results of a controlled clinical trial in patients with primitive and metastatic CNS tumours treated with combined therapy: surgery, radiotherapy, and chemotherapy (BCNU or CCNU). A total of 102 patients were treated, 50 with BCNU, and 52 with CCNU. The overall response (R. + P.R.) was 68% for the BCNU group, and 65% for the CCNU group. No significant differences were found between the two types of treatment, either in terms of response or in terms of quality and length of survival.

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Year:  1978        PMID： 356524     DOI： 10.1007/bf01811342

Source DB:  PubMed          Journal:  Acta Neurochir (Wien)        ISSN： 0001-6268            Impact factor:   2.216


  13 in total

1.  Third national cancer survey: incidence data.

Authors: 
Journal:  Natl Cancer Inst Monogr       Date:  1975-03

2.  Nucleic acid synthesis and the division cycle in x-irradiated L-strain mouse cells.

Authors:  G F WHITMORE; C P STANNERS; J E TILL; S GULYAS
Journal:  Biochim Biophys Acta       Date:  1961-02-12

3.  The use of BCNU in chemotherapy of tumors of the central nervous system.

Authors:  G Introzzi; P Paoletti; S Pezzotta; G Robustelli della Cuna; R Rodriguez y Baena
Journal:  J Neurosurg Sci       Date:  1975 Oct-Dec       Impact factor: 2.279

Review 4.  Nitrosoureas in central nervous system tumors.

Authors:  M D Walker
Journal:  Cancer Chemother Rep 3       Date:  1973-05

5.  Comparison of postoperative irradiation alone and in combination with BCNU (NSC-409962) in the management of malignant gliomas.

Authors:  S A Armentrout; E Foltz; H Vermund; P T Otis
Journal:  Cancer Chemother Rep       Date:  1974 Nov-Dec

6.  Brain tumor chemotherapy with mithramycin and vincristine.

Authors:  J Mealey; T T Chen; E Pedlow
Journal:  Cancer       Date:  1970-08       Impact factor: 6.860

7.  Clinical studies with 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC 79037).

Authors:  H H Hansen; O S Selawry; F M Muggia; M D Walker
Journal:  Cancer Res       Date:  1971-03       Impact factor: 12.701

8.  Clinical studies in malignant gliomas and their treatment with the nitrosoureas.

Authors:  M D Walker; E A Gehan
Journal:  Cancer Treat Rep       Date:  1976-06

9.  Controlled study of CCNU and radiation therapy in malignant astrocytoma.

Authors:  T J Reagan; H F Bisel; D S Childs; D D Layton; A L Rhoton; W F Taylor
Journal:  J Neurosurg       Date:  1976-02       Impact factor: 5.115

10.  Combination chemotherapy with 1-(2-chloroethyl-3-cyclohexyl-1-nitrosourea) (CCNU), vincristine and methotrexate in primary and metastatic brain tumors--a preliminary report.

Authors:  J Hildebrand; J Brihaye; L Wagenknecht; J Michel; Y Kenis
Journal:  Eur J Cancer       Date:  1973-09       Impact factor: 9.162
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  6 in total

Review 1.  Neuro-oncology index and review (adult primary brain tumors). Radiotherapy, chemotherapy, immunotherapy, photodynamic therapy.

Authors:  M S Mahaley
Journal:  J Neurooncol       Date:  1991-10       Impact factor: 4.130

2.  Pathology of human malignant gliomas after radiation and chemotherapy.

Authors:  D Schiffer; M T Giordana; P Paoletti; R Soffietti; L Tarenzi
Journal:  Acta Neurochir (Wien)       Date:  1980       Impact factor: 2.216

3.  Radiotherapy and combination chemotherapy with carmustine, vincristine, and procarbazine (BVP) in primary brain tumors.

Authors:  G Comella; G Scoppa; M De Marco; G P Ianniello; G Melillo; F Coucourde; D Zarrilli
Journal:  J Neurooncol       Date:  1985       Impact factor: 4.130

4.  Combination chemotherapy (COMP protocol) and radiotherapy of anaplastic supratentorial gliomas.

Authors:  K Jellinger; P Kothbauer; D Volc; R Vollmer; R Weiss
Journal:  Acta Neurochir (Wien)       Date:  1979       Impact factor: 2.216

5.  Immunological monitoring of patients affected by anaplastic glioma concerning in effects of surgery, radio-, and chemotherapy. A preliminary report.

Authors:  F Servadei; R Parente; F Spagnolli; G Gaist; R Padovani; M Bucci; L Steiner
Journal:  Acta Neurochir (Wien)       Date:  1982       Impact factor: 2.216

6.  Efficacy of '8-drugs-in-one-day' combination in treatment of recurrent GBM patients.

Authors:  A Boiardi; A Silvani; I Milanesi; G Broggi; L Fariselli
Journal:  J Neurooncol       Date:  1992-02       Impact factor: 4.130
  6 in total

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