Infective endocarditis in Swedish children. II. Location, major complications, laboratory findings, delay of treatment, treatment and outcome.

66 cases of infective endocarditis (IE) during 1971-1980 were studied. The infection was in most cases located to the mitral or aortic valve. Major complications were found in 43 children. In 17 children there was a long history of infection for which medical consultation had previously been sought prior to correct diagnosis. Antibiotics were administered to 60 children, in 58 intravenously while 2 received oral therapy only. Acute surgical intervention was necessary in six children and three of these children died. In all, 15 (23%) children died as a consequence of the infection.