T J Smith1,2. 1. Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, and Division of Metabolism, Endocrinology and Diabetes, University of Michigan Medical School, Brehm Tower, 1000 Wall Street, Ann Arbor, MI, 48105, USA. terrysmi@med.umich.edu. 2. Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, 48105, USA. terrysmi@med.umich.edu.