Literature DB >> 35640879

Correction to: Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales.

Christopher A Darlow, William Hope.   

Abstract

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Year:  2022        PMID: 35640879      PMCID: PMC9244209          DOI: 10.1093/jac/dkac153

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.758


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Journal of Antimicrobial Chemotherapy, Volume 77, Issue 3, March 2022, Pages 711–718, https://doi.org/10.1093/jac/dkab468 Our original paper[1] reported values for the model parameters A and B in Table 2 incorrectly, with the values inadvertently switched. The corrected table is shown here. All models and simulations in the original paper[1] and subsequent correspondence[2] used the correct values and the conclusions of the paper remain unaltered. The correspondence received relating to the original paper[3] used the original incorrectly switched values for parameters A and B, and should be interpreted with this in mind. The online version of the article has now been corrected.
Table 2.

Median, mean and variance parameter values from the final PopPK model

ParameterMedian (95% credibility interval)MeanSD
ClStd (L/h/70 kg)24.059 (21.667–30.842)23.75910.483
VStd (L/70 kg)19.595 (18.23–21.585)22.49913.361
KCP (h−1)2.770 (1.709–4.696)5.8906.516
KPC (h−1)7.007 (2.438–13.201)11.44310.764
A0.350 (0.299–0.458)0.4000.233
B0.744 (0.695–0.790)0.6930.260

ClStd and VStd are estimated standardized clearances and volume of the central compartment values, adjusted for weight±age. KCP and KPC are kinetic constants determining movement between the central and peripheral compartments and vice versa. A and B are the estimated exponents for age and weight for clearance.

Median, mean and variance parameter values from the final PopPK model ClStd and VStd are estimated standardized clearances and volume of the central compartment values, adjusted for weight±age. KCP and KPC are kinetic constants determining movement between the central and peripheral compartments and vice versa. A and B are the estimated exponents for age and weight for clearance. The authors apologise for this error.
  3 in total

1.  Comment on: Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales.

Authors:  Joseph F Standing
Journal:  J Antimicrob Chemother       Date:  2022-06-29       Impact factor: 5.790

2.  Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales-authors' response.

Authors:  Christopher A Darlow; William Hope
Journal:  J Antimicrob Chemother       Date:  2022-06-29       Impact factor: 5.758

3.  Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales.

Authors:  Christopher A Darlow; William Hope
Journal:  J Antimicrob Chemother       Date:  2022-02-23       Impact factor: 5.790

  3 in total

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