Rehab Magdy1, Ragaey A Eid2, Mahmoud Hassan3, Mohamed Abdelghaffar4, Asmaa F El Sayed5, Zeinab Mohammed6, Mona Hussein7. 1. Department of Neurology, Faculty of Medicine, Cairo University, Cairo, Egypt. rehab.m.hassan@kasralainy.edu.eg. 2. Department of Tropical medicine (Department of Gastroenterology, Hepatology and Endemic Medicine), Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt. 3. Department of Internal medicine, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt. 4. Department of Neurology, Faculty of Medicine, Fayoum University, Fayoum, Egypt. 5. Department of Public Health and Community Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt. 6. Department of Public Health and Community Medicine, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt. 7. Department of Neurology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
Abstract
BACKGROUND: Specific dietary recommendations for migraine patients with comorbid irritable bowel syndrome (IBS) are lacking. This work aimed to study the severity scores of such two common pain-related disorders in relation to various macronutrients and micronutrients intake. METHODS: A cross-sectional study was conducted on patients with concomitant migraine and IBS. The frequency and intensity of migraine attacks and the severity of IBS were evaluated. Data on dietary intake were collected using food frequency questionnaires and 24-hour dietary recall. RESULTS: One-hundred patients with a median age of 36 years participated. The severity scores for migraine and IBS were positively correlated with fat and copper and negatively correlated with fiber and zinc intake. Copper intake was an independent predictor of the severity of both migraine and IBS (P 0.033, < 0.001). Patients with episodic migraine (n = 69) had a significantly higher frequency of cooked, fresh vegetables, and wheat bran bread intake (P 0.009, 0.004, 0.021) and lower frequency of hydrogenated oils intake (P 0.046), in comparison to patients with chronic migraine (n = 31). Patients with moderate intensity of migraine (n = 37) had a significantly higher frequency of herbal drinks intake (P 0.014) than patients with a severe intensity of migraine (n = 63). Patients with mild (n = 13) and moderate IBS (n = 41) had a significantly higher frequency of wheat bran bread and sen bread intake (P 0.003, 0.022) than patients with severe IBS (n = 46). CONCLUSION: Patients with comorbid migraine and IBS are advised to adhere to a diet low in fat and copper and rich in fiber and zinc.
BACKGROUND: Specific dietary recommendations for migraine patients with comorbid irritable bowel syndrome (IBS) are lacking. This work aimed to study the severity scores of such two common pain-related disorders in relation to various macronutrients and micronutrients intake. METHODS: A cross-sectional study was conducted on patients with concomitant migraine and IBS. The frequency and intensity of migraine attacks and the severity of IBS were evaluated. Data on dietary intake were collected using food frequency questionnaires and 24-hour dietary recall. RESULTS: One-hundred patients with a median age of 36 years participated. The severity scores for migraine and IBS were positively correlated with fat and copper and negatively correlated with fiber and zinc intake. Copper intake was an independent predictor of the severity of both migraine and IBS (P 0.033, < 0.001). Patients with episodic migraine (n = 69) had a significantly higher frequency of cooked, fresh vegetables, and wheat bran bread intake (P 0.009, 0.004, 0.021) and lower frequency of hydrogenated oils intake (P 0.046), in comparison to patients with chronic migraine (n = 31). Patients with moderate intensity of migraine (n = 37) had a significantly higher frequency of herbal drinks intake (P 0.014) than patients with a severe intensity of migraine (n = 63). Patients with mild (n = 13) and moderate IBS (n = 41) had a significantly higher frequency of wheat bran bread and sen bread intake (P 0.003, 0.022) than patients with severe IBS (n = 46). CONCLUSION: Patients with comorbid migraine and IBS are advised to adhere to a diet low in fat and copper and rich in fiber and zinc.
Authors: Karin Eva Koopman; Jan Booij; Eric Fliers; Mireille Johanna Serlie; Susanne Eva la Fleur Journal: Mol Metab Date: 2013-08-07 Impact factor: 7.422