| Literature DB >> 35636788 |
G James Rubin1, Louise E Smith2, Richard Amlot3, Nicola T Fear4, Henry Potts5, Susan Michie6.
Abstract
OBJECTIVES: To assess the percentage of people in the UK with cough, fever or loss of taste or smell who have not had a positive COVID-19 test result who had been to work, to shops, socialised or provided care to a vulnerable person in the 10 days after developing symptoms. To investigate whether these rates differed according to the type of symptom, what the participant thought the cause of their symptoms was and whether they had taken a COVID-19 test.Entities:
Keywords: COVID-19; infection control; public health
Mesh:
Year: 2022 PMID: 35636788 PMCID: PMC9152621 DOI: 10.1136/bmjopen-2021-060511
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 3.006
Behaviours among people with fever, cough or loss of taste or smell and who have not had a positive COVID-19 test
| Been out to… | |||||||||||||||||||||
| The shops for groceries/pharmacy | The shops for things other than groceries/pharmacy | Go to work (total n=356) | Meet friends or family that you don’t live with | Provide help or care for a vulnerable person | |||||||||||||||||
| No | Yes | No | Yes | No | Yes | No | Yes | No | Yes | ||||||||||||
| % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | n | ||
| Symptom | Fever | 40.7 (33.2 to 48.2) | 68 | 59.3 (51.8 to 66.8) | 99 | 48.5 (40.8 to 56.2) | 81 | 51.5 (43.8 to 59.2) | 86 | 47.5 (38.6 to 56.5) | 58 | 52.5 (43.5 to 61.4) | 64 | 50.9 (43.2 to 58.6) | 85 | 49.1 (41.4 to 56.8) | 82 | 59.9 (52.4 to 67.4) | 100 | 40.1 (32.6 to 47.6) | 67 |
| Cough | 38.5 (31.1 to 45.9) | 65 | 61.5 (54.1 to 68.9) | 104 | 55.6 (48.1 to 63.2) | 94 | 44.4 (36.8 to 51.9) | 75 | 48.8 (39.7 to 57.8) | 59 | 51.2 (42.2 to 60.3) | 62 | 52.7 (45.1 to 60.3) | 89 | 47.3 (39.7 to 54.9) | 80 | 68.6 (61.6 to 75.7) | 116 | 31.4 (24.3 to 38.4) | 53 | |
| Loss of taste/smell | 39.1 (31.5 to 46.8) | 63 | 60.9 (53.2 to 68.5) | 98 | 44.1 (36.3 to 51.9) | 71 | 55.9 (48.1 to 63.7) | 90 | 43.8 (34.4 to 53.1) | 49 | 56.3 (46.9 to 65.6) | 63 | 48.4 (40.6 to 56.2) | 78 | 51.6 (43.8 to 59.4) | 83 | 60.2 (52.6 to 67.9) | 97 | 39.8 (32.1 to 47.4) | 64 | |
| Attributed to* | COVID-19 | 41.6 (31.8 to 51.4) | 42 | 58.4 (48.6 to 68.2) | 59 | 48.5 (38.6 to 58.4) | 49 | 51.5 (41.6 to 61.4) | 52 | 51.2 (40.2 to 62.3) | 42 | 48.8 (37.7 to 59.8) | 40 | 53.5 (43.6 to 63.4) | 54 | 46.5 (36.6 to 56.4) | 47 | 59.4 (49.7 to 69.1) | 60 | 40.6 (30.9 to 50.3) | 41 |
| Infectious illness | 40.5 (35.0 to 46.0) | 125 | 59.5 (54.0 to 65.0) | 184 | 50.8 (45.2 to 56.4) | 157 | 49.2 (43.6 to 54.8) | 152 | 43.9 (37.1 to 50.6) | 93 | 56.1 (49.4 to 62.9) | 119 | 52.8 (47.2 to 58.3) | 163 | 47.2 (41.7 to 52.8) | 146 | 64.1 (58.7 to 69.5) | 198 | 35.9 (30.5 to 41.3) | 111 | |
| Non- infectious illness | 33.3 (23.2 to 43.4) | 29 | 66.7 (56.6 to 76.8) | 58 | 46.0 (35.3 to 56.7) | 40 | 54.0 (43.3 to 64.7) | 47 | 50.8 (37.9 to 63.7) | 31 | 49.2 (36.3 to 62.1) | 30 | 40.2 (29.7 to 50.7) | 35 | 59.8 (49.3 to 70.3) | 52 | 63.2 (52.9 to 73.6) | 55 | 36.8 (26.4 to 47.1) | 32 | |
| Testing uptake* | No test | 33.8 (28.4 to 39.2) | 100 | 66.2 (60.8 to 71.6) | 196 | 40.9 (35.2 to 46.5) | 121 | 59.1 (53.5 to 64.8) | 175 | 41.2 (34.6 to 47.7) | 91 | 58.8 (52.3 to 65.4) | 130 | 44.3 (38.6 to 49.9) | 131 | 55.7 (50.1 to 61.4) | 165 | 54.4 (48.7 to 60.1) | 161 | 45.6 (39.9 to 51.3) | 135 |
| LFT only | 40.2 (30 to 50.4) | 37 | 59.8 (49.6 to 70) | 55 | 60.9 (50.7 to 71) | 56 | 39.1 (29 to 49.3) | 36 | 55.2 (42.0 to 68.4) | 32 | 44.8 (31.6 to 58) | 26 | 58.7 (48.4 to 68.9) | 54 | 41.3 (31.1 to 51.6) | 38 | 81.5 (73.4 to 89.6) | 75 | 18.5 (10.4 to 26.6) | 17 | |
| PCR test | 54.1 (44.6 to 63.6) | 59 | 45.9 (36.4 to 55.4) | 50 | 63.3 (54.1 to 72.5) | 69 | 36.7 (27.5 to 45.9) | 40 | 56.6 (45.2 to 68) | 43 | 43.4 (32 to 54.8) | 33 | 61.5 (52.2 to 70.8) | 67 | 38.5 (29.2 to 47.8) | 42 | 70.6 (62.0 to 79.3) | 77 | 29.4 (20.7 to 38) | 32 | |
*Due to a technical error, one person was not asked about their symptom attribution or test type, therefore n for those analyses is 497.
LFT, lateral flow test.
Associations between activity and symptom, symptom attribution and requesting a test
| Been out to… | |||||||||||||||||||||
| The shops for groceries/pharmacy | The shops for things other than groceries/pharmacy | Go to work | Meet friends or family that you don’t live with | Provide help or care for a vulnerable person | |||||||||||||||||
| OR for going out (95% CI)† | P value | aOR for going out (95% CI)‡ § | P value | OR for going out (95% CI)† | P value | aOR for going out (95% CI)‡ § | P value | OR for going out (95% CI)¶ | P value | aOR for going out (95% CI)§** | P value | OR for going out (95% CI)† | P value | aOR for going out (95% CI)‡ § | P value | OR for going out (95% CI)† | P value | aOR for going out (95% CI) ‡§ | P value | ||
| Symptom | Fever | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – |
| Cough | 1.10 (0.71 to 1.70) | 0.67 | 1.30 (0.80 to 2.13) | 0.29 | 0.75 (0.49 to 1.15) | 0.19 | 0.93 (0.57 to 1.54) | 0.79 | 0.95 (0.58 to 1.58) | 0.85 | 1.35 (0.73 to 2.51) | 0.34 | 0.93 (0.61 to 1.43) | 0.75 | 0.95 (0.58 to 1.56) | 0.85 | 0.68 (0.44 to 1.07) | 0.09 | 0.87 (0.50 to 1.53) | 0.64 | |
| Loss of taste/smell | 1.07 (0.69 to 1.66) | 0.77 | 1.03 (0.63 to 1.7) | 0.91 | 1.19 (0.77 to 1.84) | 0.42 | 1.12 (0.67 to 1.86) | 0.66 | 1.17 (0.70 to 1.95) | 0.56 | 1.10 (0.59 to 2.04) | 0.77 | 1.10 (0.72 to 1.70) | 0.66 | 0.99 (0.60 to 1.62) | 0.96 | 0.98 (0.63 to 1.53) | 0.95 | 0.80 (0.47 to 1.37) | 0.42 | |
| Overall | χ2(2)=0.2 | 0.91 | χ2(2)=1.3 | 0.52 | χ2(2)=4.5 | 0.11 | χ2(2)=0.5 | 0.78 | χ2(2)=0.6 | 0.73 | χ2(2)=1.0 | 0.62 | χ2(2)=0.6 | 0.74 | χ2(2)=0.0 | 0.98 | χ2(2)=3.5 | 0.17 | χ2(2)=0.7 | 0.72 | |
| Attributed to† | COVID-19 | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – |
| Infectious illness | 1.05 (0.66 to 1.65) | 0.84 | 1.34 (0.80 to 2.26) | 0.27 | 0.91 (0.58 to 1.43) | 0.69 | 1.51 (0.90 to 2.55) | 0.12 | 1.34 (0.81 to 2.24) | 0.26 | 2.37 (1.26 to 4.45) | 0.008 | 1.03 (0.66 to 1.61) | 0.90 | 1.37 (0.82 to 2.31) | 0.23 | 0.82 (0.52 to 1.30) | 0.40 | 1.32 (0.76 to 2.30) | 0.32 | |
| Non- infectious illness | 1.42 (0.78 to 2.58) | 0.25 | 2.06 (1.05 to 4.05) | 0.04 | 1.11 (0.62 to 1.97) | 0.73 | 1.58 (0.81 to 3.07) | 0.18 | 1.02 (0.52 to 1.97) | 0.96 | 1.33 (0.59 to 3.02) | 0.49 | 1.71 (0.96 to 3.05) | 0.07 | 2.47 (1.27 to 4.80) | 0.008 | 0.85 (0.47 to 1.54) | 0.59 | 1.30 (0.64 to 2.63) | 0.47 | |
| Overall | χ2(2)=1.7 | 0.43 | χ2(2)=4.4 | 0.11 | χ2(2)=0.7 | 0.71 | χ2(2)=2.7 | 0.26 | χ2(2)=1.8 | 0.41 | χ2(2)=8.0 | 0.02 | χ2(2)=4.6 | 0.10 | χ2(2)=7.3 | 0.03 | χ2(2)=0.7 | 0.70 | χ2(2)=1.0 | 0.60 | |
| Testing uptake† | No test | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – | Ref | – |
| LFT only | 0.76 (0.47 to 1.23) | 0.26 | 0.84 (0.48 to 1.46) | 0.53 | 0.44 (0.28 to 0.72) | 0.001* | 0.58 (0.33 to 1.02) | 0.06 | 0.57 (0.32 to 1.02) | 0.06 | 0.87 (0.42 to 1.78) | 0.70 | 0.56 (0.35 to 0.90) | 0.02 | 0.70 (0.40 to 1.22) | 0.20 | 0.27 (0.15 to 0.48) | <0.001* | 0.40 (0.20 to 0.80) | 0.01 | |
| PCR test | 0.43 (0.28 to 0.68) | <0.001* | 0.44 (0.27 to 0.74) | 0.002* | 0.4 (0.25 to 0.63) | <0.001* | 0.38 (0.22 to 0.65) | <0.001* | 0.54 (0.32 to 0.91) | 0.02 | 0.49 (0.25 to 0.96) | 0.04 | 0.50 (0.32 to 0.78) | 0.002* | 0.47 (0.28 to 0.80) | 0.005 | 0.50 (0.31 to 0.79) | 0.004 | 0.43 (0.24 to 0.78) | 0.005 | |
| Overall | χ2(2)=13.5 | 0.001* | χ2(2)=9.6 | 0.008 | χ2(2)=21.5 | <0.001* | χ2(2)=13.2 | 0.001* | χ2(2)=7.3 | 0.03 | χ2(2)=4.4 | 0.11 | χ2(2)=12.2 | 0.002* | χ2(2)=8.0 | 0.02 | χ2(2)=24.3 | <0.001* | χ2(2)=11.8 | 0.003 | |
*P value≤0.002.
†n=497 (99.8% valid responses).
‡n=462 (92.8% valid responses).
§Adjusting for all socio-demographic characteristics.
¶n=355 (99.7% valid responses).
**n=337 (94.7% valid responses).
LFT, lateral flow test.