Sisi Cao1, Connie M Weaver2,3. 1. Human Nutrition Program, The Ohio State University, Columbus, OH, USA. 2. Weaver and Associates Consulting LLC, Colorado Springs, CO, USA. weaverconnie1995@gmail.com. 3. Department of Exercise and Nutritional Sciences, San Diego State University, 5500 Campanile, San Diego, CA, 92182, USA. weaverconnie1995@gmail.com.
Abstract
PURPOSE OF REVIEW: Interest in preventing atherosclerosis and cardiovascular disease extends beyond essential nutrients and dietary patterns. This article reviews the potential for bioactive compounds to play a role in prevention and the recent process in guidance for developing policy for bioactives. RECENT FINDINGS: A framework for developing recommended intakes of bioactives dietary substances was recently developed and the first guideline expected is for a bioactive targeted for cardiometabolic health. Bioactives target endothelial health, the gut microbiome, serum lipids, blood pressure, inflammation, and oxidative stress. The evidence base is growing and will be enhanced further with the discovery of good biomarkers of exposure and health outcomes. A robust evidence base is essential to develop policy and influence clinical practice for bioactives, an exciting and growing area of research.
PURPOSE OF REVIEW: Interest in preventing atherosclerosis and cardiovascular disease extends beyond essential nutrients and dietary patterns. This article reviews the potential for bioactive compounds to play a role in prevention and the recent process in guidance for developing policy for bioactives. RECENT FINDINGS: A framework for developing recommended intakes of bioactives dietary substances was recently developed and the first guideline expected is for a bioactive targeted for cardiometabolic health. Bioactives target endothelial health, the gut microbiome, serum lipids, blood pressure, inflammation, and oxidative stress. The evidence base is growing and will be enhanced further with the discovery of good biomarkers of exposure and health outcomes. A robust evidence base is essential to develop policy and influence clinical practice for bioactives, an exciting and growing area of research.
Authors: Joram M Posma; Isabel Garcia-Perez; Gary Frost; Ghadeer S Aljuraiban; Queenie Chan; Linda Van Horn; Martha Daviglus; Jeremiah Stamler; Elaine Holmes; Paul Elliott; Jeremy K Nicholson Journal: Nat Food Date: 2020-06-22
Authors: Kelsey M Mangano; Sabrina E Noel; Chao-Qiang Lai; Jacob J Christensen; Jose M Ordovas; Bess Dawson-Hughes; Katherine L Tucker; Laurence D Parnell Journal: Bone Date: 2020-12-02 Impact factor: 4.398
Authors: Dagfinn Aune; Edward Giovannucci; Paolo Boffetta; Lars T Fadnes; NaNa Keum; Teresa Norat; Darren C Greenwood; Elio Riboli; Lars J Vatten; Serena Tonstad Journal: Int J Epidemiol Date: 2017-06-01 Impact factor: 7.196
Authors: Allison A Yates; Johanna T Dwyer; John W Erdman; Janet C King; Barbara J Lyle; Barbara O Schneeman; Connie M Weaver Journal: Adv Nutr Date: 2021-07-30 Impact factor: 8.701