Literature DB >> 35633402

Outcomes of octogenarians undergoing holmium laser enucleation of prostate.

Joshua Heiman1, Deepak Agarwal2, Sarah Komanapalli2, Charles Nottingham2, Tim Large2, Amy Krambeck2, Marcelino Rivera2.   

Abstract

PURPOSE: Holmium laser enucleation of prostate (HoLEP) is an effective surgical procedure in men with BPH. Due to the increase in the use of medical therapy for BPH related lower urinary symptoms more octogenarians are presenting in a delayed fashion with significant symptoms and urinary retention. We evaluate the feasibility and safety of octogenarians undergoing HoLEP.
METHODS: We performed a retrospective review of HoLEPs at our institution from July 2018 to December 2019. Patients were stratified into two groups based on age: < 80 and ≥ 80.
RESULTS: A total of 458 patients were identified, with 74 (16.2%) ≥ 80. In patients ≥ 80, prostate volume was higher (p < 0.0005), there was a higher rate of antiplatelet/anticoagulation (p = 0.029) use, and a lower rate of alpha-blocker use (p = 0.0016). As expected, ASA scores which correlate with increasing number of concomitant diseases were greater in the ≥ 80 cohort (p = 0.016). There was no significant difference in intraoperative complications (p = 0.14), 90 day complication (p = 0.34), readmission rates (p = 0.425) or emergency room visits between groups (p = 0.15).
CONCLUSIONS: Despite higher medical comorbidities and increased rates of anticoagulation in octogenarians, there is no increase in operative or postoperative complication rates. Age alone should not be used as exclusion criteria for HoLEP.
© 2022. This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.

Entities:  

Keywords:  BPH; HoLEP; Octogenarian; Surgery

Mesh:

Substances:

Year:  2022        PMID: 35633402     DOI: 10.1007/s00345-022-04053-9

Source DB:  PubMed          Journal:  World J Urol        ISSN: 0724-4983            Impact factor:   4.226


  15 in total

1.  The clinical value of holmium laser enucleation of the prostate in octogenarians.

Authors:  Alexander Tamalunas; Thilo Westhofen; Melanie Schott; Patrick Keller; Michael Atzler; Christian G Stief; Giuseppe Magistro
Journal:  Low Urin Tract Symptoms       Date:  2020-12-01       Impact factor: 1.592

Review 2.  The Epidemiology of Benign Prostatic Hyperplasia Associated with Lower Urinary Tract Symptoms: Prevalence and Incident Rates.

Authors:  Kathryn Brigham Egan
Journal:  Urol Clin North Am       Date:  2016-08       Impact factor: 2.241

Review 3.  The natural history of benign prostatic hyperplasia.

Authors:  John M Fitzpatrick
Journal:  BJU Int       Date:  2006-04       Impact factor: 5.588

Review 4.  Evidence-based outcomes of holmium laser enucleation of the prostate.

Authors:  Tim Large; Amy E Krambeck
Journal:  Curr Opin Urol       Date:  2018-05       Impact factor: 2.309

5.  Are indications for prostatectomy in octogenarians the same as for younger men?

Authors:  Andrei Nadu; Nicola J Mabjeesh; Jacob Ben-Chaim; Issac Kaver; Haim Matzkin; Alexander Greenstein
Journal:  Int Urol Nephrol       Date:  2004       Impact factor: 2.370

6.  Transurethral laser surgery for benign prostate hyperplasia in octogenarians: safety and outcomes.

Authors:  Ahmed M Elshal; Hazem M Elmansy; Mostafa M Elhilali
Journal:  Urology       Date:  2013-01-16       Impact factor: 2.649

7.  Comparative Study of Holmium Laser Enucleation of the Prostate With MOSES Enabled Pulsed Laser Modulation.

Authors:  Tim Large; Charles Nottingham; Christa Stoughton; James Williams; Amy Krambeck
Journal:  Urology       Date:  2019-11-30       Impact factor: 2.649

Review 8.  A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update.

Authors:  Jean-Nicolas Cornu; Sascha Ahyai; Alexander Bachmann; Jean de la Rosette; Peter Gilling; Christian Gratzke; Kevin McVary; Giacomo Novara; Henry Woo; Stephan Madersbacher
Journal:  Eur Urol       Date:  2014-06-25       Impact factor: 20.096

Review 9.  Epidemiology of clinical benign prostatic hyperplasia.

Authors:  Kok Bin Lim
Journal:  Asian J Urol       Date:  2017-06-09

10.  Holmium Laser Enucleation of the Prostate is Safe for Patients Above 80 Years: A Prospective Study.

Authors:  Songzhe Piao; Min Soo Choo; Myong Kim; Ho Joon Jeon; Seung-June Oh
Journal:  Int Neurourol J       Date:  2016-06-24       Impact factor: 2.835

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