Literature DB >> 35633238

Evans Syndrome: A Case Report.

Sanam Dhakal1, Sulochana Neupane1, Ankit Mandal1, Surya Bahadur Parajuli2, Sulav Sapkota3.   

Abstract

Evans syndrome is defined as the concomitant or sequential association of warm autoimmune hemolytic anaemia with immune thrombocytopenia, and less frequently autoimmune neutropenia. It is associated with non-cross-reacting auto-antibodies directed against antigens specific to red blood cells, platelets or neutrophils. Clinical symptoms could be related to hemolysis and thrombocytopenia. Evans syndrome is a rare diagnosis of exclusion. The first-line treatment of Evans syndrome is intravenous corticosteroids or intravenous immunoglobulins and second-line treatment with rituximab or splenectomy for those who are refractory to steroids. Here is a case of a fifty-year-old- female who presented with bleeding from the mouth and gums, bluish patches over the shin and trunk along with generalised weakness and severe backache. We are interested in reporting this case because the presentation of patients with such scenarios on our part will compel the treating physician to overlook Evans syndrome and get it underdiagnosed. Keywords: case reports; immunoglobulins; neutropenia; thrombocytopenia.

Entities:  

Mesh:

Year:  2022        PMID: 35633238      PMCID: PMC9252215          DOI: 10.31729/jnma.7421

Source DB:  PubMed          Journal:  JNMA J Nepal Med Assoc        ISSN: 0028-2715            Impact factor:   0.556


  3 in total

Review 1.  Evans' syndrome in pregnancy: a systematic literature review and two new cases.

Authors:  Eleftheria Lefkou; Catherine Nelson-Piercy; Beverley J Hunt
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2009-12-23       Impact factor: 2.435

Review 2.  Evans' Syndrome: From Diagnosis to Treatment.

Authors:  Sylvain Audia; Natacha Grienay; Morgane Mounier; Marc Michel; Bernard Bonnotte
Journal:  J Clin Med       Date:  2020-11-27       Impact factor: 4.241

Review 3.  Evans syndrome: clinical perspectives, biological insights and treatment modalities.

Authors:  José Carlos Jaime-Pérez; Patrizia Elva Aguilar-Calderón; Lorena Salazar-Cavazos; David Gómez-Almaguer
Journal:  J Blood Med       Date:  2018-10-10
  3 in total
  1 in total

1.  Unexpected Thrombocytopenia in a Parturient With Evans Syndrome Complicated by COVID-19 Infection.

Authors:  Mohamed Fayed; Shuchi Jain; Nyla Leonardi; Joshua Younger
Journal:  Cureus       Date:  2022-07-28
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.