Literature DB >> 35628670

Correction: Rondinone et al. Extensive Placental Methylation Profiling in Normal Pregnancies. Int. J. Mol. Sci. 2021, 22, 2136.

Ornella Rondinone1, Alessio Murgia1, Jole Costanza1, Silvia Tabano2,3, Margherita Camanni1, Luigi Corsaro4, Laura Fontana1,5, Patrizia Colapietro2, Luciano Calzari6, Silvia Motta1, Carlo Santaniello1, Tatjana Radaelli7, Enrico Ferrazzi7,8, Silvano Bosari9, Davide Gentilini4,6, Silvia Maria Sirchia5, Monica Miozzo1,5.   

Abstract

In the original publication [...].

Entities:  

Year:  2022        PMID: 35628670      PMCID: PMC9140439          DOI: 10.3390/ijms23105298

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN: 1422-0067            Impact factor:   6.208


In the original publication [1], there was a mistake in Table 2 and Table 3 as published. In the p-value column, a minus sign was missing at the exponent. The corrected Table 2 and Table 3 appear below. The authors apologize for any inconvenience caused and state that the results and scientific conclusions are unaffected by these changes. The original publication has also been updated.
Table 2

Diseases or Functions Annotation from IPA Core Analysis on given gene datasets. The top 10 most significant annotations are shown.

A
Diseases or Functions Annotation p-Value
Leukocyte migration1.52 × 10−16
Cell movement of lymphocytes5.05 × 10−14
Cell movement of mononuclear leukocytes6.30 × 10−14
Quantity of leukocytes7.50 × 10−14
Lymphocyte migration9.59 × 10−14
Quantity of lymphatic system cells1.97 × 10−13
Quantity of lymphocytes5.29 × 10−13
Cell movement of leukocytes6.80 × 10−13
Proliferation of blood cells1.21 × 10−12
Proliferation of immune cells1.62 × 10−12
B
Diseases or Functions Annotation p-Value
Cutaneous melanoma1.52 × 10−12
Skin tumor5.94 × 10−12
Melanoma1.01 × 10−11
Skin cancer1.20 × 10−11
Malignant neuroendocrine neoplasm2.45 × 10−7
Small cell lung carcinoma3.07 × 10−7
Olfactory response3.73 × 10−7
Neuroendocrine tumor4.48 × 10−7
Extrapancreatic neuroendocrine tumor5.84 × 10−7
Blue round small cell tumor7.16 × 10−6

(A) Functions identified from gene promoters methylated in the placenta but not in cord blood. (B) Functions identified from gene promoters methylated in cord blood but not in the placenta.

Table 3

Diseases or Functions Annotations in common between methylation-profiling microarray data and targeted methylation sequencing data (data from IPA Core Analysis).

A
Diseases or Functions Annotation p-Value (Microarray) p-Value (Methyl-Seq)
Leukocyte migration2.93 × 10−264.53 × 10−7
Quantity of lymphatic system cells3.30 × 10−25 4.34 × 10−6
Quantity of leukocytes1.51 × 10−25 3.42 × 10−6
Quantity of lymphocytes1.53 × 10−24 4.75 × 10−6
Cell movement of leukocytes5.69 × 10−23 1.38 × 10−10
Activation of cells2.86 × 10−225.05 × 10−14
Migration of cells1.08 × 10−217.35 × 10−7
Proliferation of lymphatic system cells1.68 × 10−211.62 × 10−6
Proliferation of lymphocytes5.96 × 10−212.09 × 10−6
Proliferation of immune cells3.46 × 10−201.58 × 10−6
B
Diseases or Functions Annotation p-Value (Microarray) p-Value (Methyl-Seq)
Cross-linkage of protein1.60 × 10−48.28 × 10−4
Skin carcinoma7.37 × 10−4 3.95 × 10−3
Skin squamous cell carcinoma9.61 × 10−42.69 × 10−4
Relaxation of heart ventricle1.03 × 10−35.24 × 10−3
Surface area of ventricular myocytes1.22 × 10−36.15 × 10−3
Gastro-esophageal carcinoma3.77 × 10−32.78 × 103
Chemosensitivity of glioblastoma cells4.03 × 10−39.20 × 10−3
Pancreatic lesion5.88 × 10−36.34 × 10−3
Formation of solid tumor5.90 × 10−31.74 × 10−3

(A) Top 10 functions identified from gene promoters methylated in placenta but not in cord blood. (B) Functions identified from gene promoters methylated in cord blood but not in placenta. (Only 9 common annotations were found.)

  1 in total

1.  Extensive Placental Methylation Profiling in Normal Pregnancies.

Authors:  Ornella Rondinone; Alessio Murgia; Jole Costanza; Silvia Tabano; Margherita Camanni; Luigi Corsaro; Laura Fontana; Patrizia Colapietro; Luciano Calzari; Silvia Motta; Carlo Santaniello; Tatjana Radaelli; Enrico Ferrazzi; Silvano Bosari; Davide Gentilini; Silvia Maria Sirchia; Monica Miozzo
Journal:  Int J Mol Sci       Date:  2021-02-21       Impact factor: 6.208

  1 in total

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