| Literature DB >> 35628670 |
Ornella Rondinone1, Alessio Murgia1, Jole Costanza1, Silvia Tabano2,3, Margherita Camanni1, Luigi Corsaro4, Laura Fontana1,5, Patrizia Colapietro2, Luciano Calzari6, Silvia Motta1, Carlo Santaniello1, Tatjana Radaelli7, Enrico Ferrazzi7,8, Silvano Bosari9, Davide Gentilini4,6, Silvia Maria Sirchia5, Monica Miozzo1,5.
Abstract
In the original publication [...].Entities:
Year: 2022 PMID: 35628670 PMCID: PMC9140439 DOI: 10.3390/ijms23105298
Source DB: PubMed Journal: Int J Mol Sci ISSN: 1422-0067 Impact factor: 6.208
Diseases or Functions Annotation from IPA Core Analysis on given gene datasets. The top 10 most significant annotations are shown.
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| Leukocyte migration | 1.52 × 10−16 |
| Cell movement of lymphocytes | 5.05 × 10−14 |
| Cell movement of mononuclear leukocytes | 6.30 × 10−14 |
| Quantity of leukocytes | 7.50 × 10−14 |
| Lymphocyte migration | 9.59 × 10−14 |
| Quantity of lymphatic system cells | 1.97 × 10−13 |
| Quantity of lymphocytes | 5.29 × 10−13 |
| Cell movement of leukocytes | 6.80 × 10−13 |
| Proliferation of blood cells | 1.21 × 10−12 |
| Proliferation of immune cells | 1.62 × 10−12 |
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| Cutaneous melanoma | 1.52 × 10−12 |
| Skin tumor | 5.94 × 10−12 |
| Melanoma | 1.01 × 10−11 |
| Skin cancer | 1.20 × 10−11 |
| Malignant neuroendocrine neoplasm | 2.45 × 10−7 |
| Small cell lung carcinoma | 3.07 × 10−7 |
| Olfactory response | 3.73 × 10−7 |
| Neuroendocrine tumor | 4.48 × 10−7 |
| Extrapancreatic neuroendocrine tumor | 5.84 × 10−7 |
| Blue round small cell tumor | 7.16 × 10−6 |
(A) Functions identified from gene promoters methylated in the placenta but not in cord blood. (B) Functions identified from gene promoters methylated in cord blood but not in the placenta.
Diseases or Functions Annotations in common between methylation-profiling microarray data and targeted methylation sequencing data (data from IPA Core Analysis).
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| Leukocyte migration | 2.93 × 10−26 | 4.53 |
| Quantity of lymphatic system cells | 3.30 | 4.34 |
| Quantity of leukocytes | 1.51 × 10−25 | 3.42 |
| Quantity of lymphocytes | 1.53 | 4.75 |
| Cell movement of leukocytes | 5.69 | 1.38 |
| Activation of cells | 2.86 | 5.05 |
| Migration of cells | 1.08 | 7.35 |
| Proliferation of lymphatic system cells | 1.68 | 1.62 |
| Proliferation of lymphocytes | 5.96 | 2.09 |
| Proliferation of immune cells | 3.46 | 1.58 |
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| Cross-linkage of protein | 1.60 × 10−4 | 8.28 × 10−4 |
| Skin carcinoma | 7.37 × 10−4 | 3.95 × 10−3 |
| Skin squamous cell carcinoma | 9.61 × 10−4 | 2.69 × 10−4 |
| Relaxation of heart ventricle | 1.03 × 10−3 | 5.24 × 10−3 |
| Surface area of ventricular myocytes | 1.22 × 10−3 | 6.15 × 10−3 |
| Gastro-esophageal carcinoma | 3.77 × 10−3 | 2.78 × 10−3 |
| Chemosensitivity of glioblastoma cells | 4.03 × 10−3 | 9.20 × 10−3 |
| Pancreatic lesion | 5.88 × 10−3 | 6.34 × 10−3 |
| Formation of solid tumor | 5.90 × 10−3 | 1.74 × 10−3 |
(A) Top 10 functions identified from gene promoters methylated in placenta but not in cord blood. (B) Functions identified from gene promoters methylated in cord blood but not in placenta. (Only 9 common annotations were found.)