Literature DB >> 3562789

Endothelial alkaline phosphatase activity loss as an early stage in the development of radiation-induced heart disease in rats.

S Lauk.   

Abstract

Alkaline phosphatase activity of capillary endothelial cells in the heart of Wistar and Sprague-Dawley rats was studied sequentially after single doses of 10, 15, 20, or 25 Gy. Following irradiation capillary density and alkaline phosphatase activity were focally lost before myocardial degeneration or clinical symptoms of heart disease developed. Recovery from both changes took place after doses of 10 or 15 Gy. The decrease in capillary density and enzyme activity showed the same strain difference in latency times and in the extent of the lesions as previously described for pathological and clinical signs of heart disease.

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Year:  1987        PMID： 3562789

Source DB:  PubMed          Journal:  Radiat Res        ISSN： 0033-7587            Impact factor:   2.841


  9 in total

1.  10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model.

Authors:  John E Baker; Brian L Fish; Jidong Su; Steven T Haworth; Jennifer L Strande; Richard A Komorowski; Raymond Q Migrino; Anil Doppalapudi; Leanne Harmann; X Allen Li; John W Hopewell; John E Moulder
Journal:  Int J Radiat Biol       Date:  2009-12       Impact factor: 2.694

2.  Single exposure to radiation produces early anti-angiogenic effects in mouse aorta.

Authors:  Kevin G Soucy; David O Attarzadeh; Raghav Ramachandran; Patricia A Soucy; Lewis H Romer; Artin A Shoukas; Dan E Berkowitz
Journal:  Radiat Environ Biophys       Date:  2010-04-18       Impact factor: 1.925

3.  Cardiac and Renal Delayed Effects of Acute Radiation Exposure: Organ Differences in Vasculopathy, Inflammation, Senescence and Oxidative Balance.

Authors:  Joseph L Unthank; Miguel Ortiz; Hina Trivedi; Louis M Pelus; Carol H Sampson; Rajendran Sellamuthu; Alexa Fisher; Hui Lin Chua; Artur Plett; Christie M Orschell; Eric P Cohen; Steven J Miller
Journal:  Radiat Res       Date:  2019-03-22       Impact factor: 2.841

Review 4.  Effects of ionizing radiation on the heart.

Authors:  Marjan Boerma; Vijayalakshmi Sridharan; Xiao-Wen Mao; Gregory A Nelson; Amrita K Cheema; Igor Koturbash; Sharda P Singh; Alan J Tackett; Martin Hauer-Jensen
Journal:  Mutat Res Rev Mutat Res       Date:  2016-07-10       Impact factor: 5.657

5.  A priming dose of protons alters the early cardiac cellular and molecular response to (56)Fe irradiation.

Authors:  Samy S Ramadan; Vijayalakshmi Sridharan; Igor Koturbash; Isabelle R Miousse; Martin Hauer-Jensen; Gregory A Nelson; Marjan Boerma
Journal:  Life Sci Space Res (Amst)       Date:  2015-12-14

6.  Hepatocyte growth factor protects endothelial cells against gamma ray irradiation-induced damage.

Authors:  Shun-Ying Hu; Hai-Feng Duan; Qing-Fang Li; Yue-Feng Yang; Jin-Long Chen; Li-Sheng Wang; Hua Wang
Journal:  Acta Pharmacol Sin       Date:  2009-09-14       Impact factor: 6.150

Review 7.  Hydrogen as a new class of radioprotective agent.

Authors:  Liren Qian; Jianliang Shen; Yunhai Chuai; Jianming Cai
Journal:  Int J Biol Sci       Date:  2013-09-14       Impact factor: 6.580

Review 8.  Cardiovascular diseases related to ionizing radiation: The risk of low-dose exposure (Review).

Authors:  Bjorn Baselet; Charlotte Rombouts; Abderrafi Mohammed Benotmane; Sarah Baatout; An Aerts
Journal:  Int J Mol Med       Date:  2016-10-17       Impact factor: 4.101

Review 9.  Myocardial Disease and Long-Distance Space Travel: Solving the Radiation Problem.

Authors:  Manon Meerman; Tom C L Bracco Gartner; Jan Willem Buikema; Sean M Wu; Sailay Siddiqi; Carlijn V C Bouten; K Jane Grande-Allen; Willem J L Suyker; Jesper Hjortnaes
Journal:  Front Cardiovasc Med       Date:  2021-02-12
  9 in total

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