Literature DB >> 356265

Unusual antibody-induced modulation of surface antigens in the cell coat of a bloodstream trypanosome.

M S Giannini, P A D'Alesandro.   

Abstract

Unlike other eukaryotic cells, Trypanosoma lewisi forms caps at 0 degrees C when incubated with rabbit immunoglobulin G(IgG) directed against surface IgG from the rat host. The host IgG, which is specific for parasite antigens, probably does not cause capping of these antigens in vivo, since trypanosomes treated with Fab fragments directed against rat IgG are uniformly labeled and do not cap at 0 degrees C or 37 degrees C.

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Year:  1978        PMID: 356265     DOI: 10.1126/science.356265

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  Inactivation or elimination of potentially trypanolytic, complement-activating immune complexes by pathogenic trypanosomes.

Authors:  A E Balber; J D Bangs; S M Jones; R L Proia
Journal:  Infect Immun       Date:  1979-06       Impact factor: 3.441

2.  Surface-associated host proteins on virulent Treponema pallidum.

Authors:  J F Alderete; J B Baseman
Journal:  Infect Immun       Date:  1979-12       Impact factor: 3.441

3.  Host plasma proteins on the surface of pathogenic Trichomonas vaginalis.

Authors:  K M Peterson; J F Alderete
Journal:  Infect Immun       Date:  1982-08       Impact factor: 3.441

  3 in total

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