| Literature DB >> 35625951 |
Yuan Liu1, Yaqin Tang1, Xing Tang2, Mengqi Wu1, Shengjie Hou1, Xiaohua Liu1, Jing Li1, Meichun Deng3, Shuaiqin Huang1, Liping Jiang1,4.
Abstract
In the original publication, there were mistakes in Figure 3C, Figure 6B and Figure S2A,B as published [...].Entities:
Year: 2022 PMID: 35625951 PMCID: PMC9185831 DOI: 10.3390/biomedicines10051176
Source DB: PubMed Journal: Biomedicines ISSN: 2227-9059
Figure 3Effects of XYP1 on the invasion of T. gondii tachyzoites. Tachyzoites were pre-treated with DMEM (the negative control), SFZ (the positive control), and two-fold serial dilutions of XYP1 before exposure to host cells, respectively. Statistical results were expressed as the invasion rate (A). HFFs in DMEM group and XYP1 group (10 μΜ) were observed by a light microscope (40×) (B). HFFs in DMEM group and XYP1 group (10 μΜ) were also observed by a light microscope (100×) (C). The means were determined by values obtained from three independent experiments (χ2-tests). * p < 0.05, ** p < 0.01 and *** p < 0.001 in comparison with control. Scale bars = 5 μm (B); 25 μm (C).
Figure 6Ultrastructural effects of XYP1 on T. gondii tachyzoites as visualized by TEM. Parasites treated with DMEM were defined as the negative control (A,B). Tachyzoites were exposed to 10 μM XYP1 for 2 h (C–F). Abbreviations in B: C, conoid; CM, cell membrane; DG, dense granule; Go, golgi complex; LB, lipid body; MN, microneme; N, nucleus; NM, nuclear membrane. Scale bars = 10 μm (A); 2 μm (B–D); 1 μm (E,F).