| Literature DB >> 3562264 |
H Nakane, J Balzarini, E De Clercq, K Ono.
Abstract
Evans Blue, an anionic dye which has been found to inhibit the replication of human immunodeficiency virus, proved also inhibitory to the DNA polymerases alpha and beta. The mode of inhibition was competitive with respect to the template X primer, and noncompetitive with respect to the deoxynucleoside triphosphate substrates. The inhibitory effect of Evans Blue on DNA polymerases is discussed in relation to that of suramin.Entities:
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Year: 1986 PMID： 3562264
Source DB: PubMed Journal: Nucleic Acids Symp Ser ISSN： 0261-3166