Photoinitiated Polymerization-Induced Self-Assembly via Visible Light-Induced RAFT-Mediated Emulsion Polymerization.

Aqueous emulsion polymerization is one of the most commonly used techniques in industry for the production of polymer latexes. In this contribution, we present photoinitiated polymerization-induced self-assembly (photo-PISA) based on aqueous visible light-induced reversible addition-fragmentation chain transfer (RAFT)-mediated emulsion polymerization at room temperature. A wide range of morphologies including spheres, worms, and vesicles have been achieved at room temperature by modulating reaction parameters. Additionally, this method enables access to inorganic nanoparticles-loaded vesicles by adding inorganic nanoparticles at the beginning of the polymerization. Finally, an oxygen-tolerant RAFT-mediated emulsion polymerization has been developed, allowing the synthesis of polymer nano-objects at low volumes (e.g., in a 96-well plate). This study is expected to expand the scope of photo-PISA for the preparation of various block copolymer nano-objects in water at room temperature.