Literature DB >> 3561928

In vivo effect of didemnin B on two tumors of the rat.

V Fimiani.   

Abstract

Didemnin B administered at a dose of 0.06 mg/kg, highest nontoxic dose for the rat, shows a high antitumor activity against Yoshida ascites tumor only after intraperitoneal injection of the drug; supplied by other routes both against T8 sarcoma of Guérin and Yoshida ascites tumor is ineffective.

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Year:  1987        PMID: 3561928     DOI: 10.1159/000226441

Source DB:  PubMed          Journal:  Oncology        ISSN: 0030-2414            Impact factor:   2.935


  1 in total

1.  Phase II clinical and pharmacological study of didemnin B in patients with metastatic breast cancer.

Authors:  J A Benvenuto; R A Newman; G S Bignami; T J Raybould; M N Raber; L Esparza; R S Walters
Journal:  Invest New Drugs       Date:  1992-07       Impact factor: 3.850

  1 in total

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