Designing Solute-Tailored Selectivity in Membranes: Perspectives for Water Reuse and Resource Recovery.

Treatment of nontraditional source waters (e.g., produced water, municipal and industrial wastewaters, agricultural runoff) offers exciting opportunities to expand water and energy resources via water reuse and resource recovery. While conventional polymer membranes perform water/ion separations well, they do not provide solute-specific separation, a key component for these treatment opportunities. Herein, we discuss the selectivity limitations plaguing all conventional membranes, which include poor removal of small, neutral solutes and insufficient discrimination between ions of the same valence. Moreover, we present synthetic approaches for solute-tailored selectivity including the incorporation of single-digit nanopores and solute-selective ligands into membranes. Recent progress in these areas highlights the need for fundamental studies to rationally design membranes with selective moieties achieving desired separations.