| Literature DB >> 35615582 |
In Kwon Choi1, Eroma Abeysinghe2, Eric Coulter2, Suresh Marru2, Marlon Pierce2, Xiaowen Liu1.
Abstract
Top-down mass spectrometry-based proteomics has become the method of choice for identifying and quantifying intact proteoforms in biological samples. We present a web-based gateway for TopPIC suite, a widely used software suite consisting of four software tools for top-down mass spectrometry data interpretation: TopFD, TopPIC, TopMG, and TopDiff. The gateway enables the community to use heterogeneous collection of computing resources that includes high performance computing clusters at Indiana University and virtual clusters on XSEDE's Jetstream Cloud resource for top-down mass spectral data analysis using TopPIC suite. The gateway will be a useful resource for proteomics researchers and students who have limited access to high-performance computing resources or who are not familiar with interacting with server-side supercomputers.Entities:
Keywords: Apache Airavata; Applied computing → Bioinformatics; Information systems → Computing platforms; Proteomics; SciGaP; Science Gateways; Top-down mass spectrometry; XSEDE
Year: 2020 PMID： 35615582 PMCID： PMC9128478 DOI： 10.1145/3311790.3400853
Source DB: PubMed Journal: PEARC20 (2020)